儿童难治性癫痫术后认知功能变化的研究进展  

Advances in postoperative cognitive changes in children with refractory epilepsy

作　　者：阎泓羽 冯硕[2] 刘婉婷 高彦彦 姬辛娜[2] 陈金晓 陈倩[1,2] Yan Hongyu;Feng Shuo;Liu Wanting;Gao Yanyan;Ji Xinna;Chen Jinxiao;Chen Qian(Department of Neurology,Capital Institute of Pediatrics-Peking University Teaching Hospital,Beijing 100020,China;Department of Neurology,Children's Hospital Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]北京大学首都儿科研究所教学医院神经内科,北京100020 [2]首都儿科研究所附属儿童医院神经内科,北京100020

出　　处：《中国医学前沿杂志（电子版）》2024年第4期68-72,共5页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

基　　金：首都卫生发展科研专项项目(2022-2Z-2104)。

摘　　要：难治性癫痫儿童常伴有不同程度的认知功能障碍,部分患儿需进行癫痫外科手术治疗。随访研究儿童难治性癫痫术后认知功能的变化情况,有助于术前辅助临床决策。多项研究结果显示,术后多数患儿整体认知功能发展较术前无下降甚至改善,术前智商/发育商水平、抗癫痫药物数量及癫痫发作等多因素与术后认知功能预后相关。本文综述儿童难治性癫痫术后认知功能研究进展。Children with refractory epilepsy often experience varying degrees of cognitive dysfunction,and some may require epileptic surgery.Follow-up studies on the changes in cognitive function after surgery in children with refractory epilepsy are beneficial for assisting preoperative clinical decisions.Multiple research findings indicate that,in the majority of cases,the overall cognitive function in children tends to either remain stable or improve after surgery,as compared to preoperative levels.Factors such as preoperative IQ/DQ levels,the quantity of antiepileptic drugs used,and the severity of epileptic seizures are associated with the prognosis of cognitive function postoperatively.This article reviews the research progress on postoperative cognitive function in children with refractory epilepsy.

关 键 词：儿童 难治性 癫痫手术 认知功能 

分 类 号：R726.5[医药卫生—儿科]