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作 者:潘宁静 朱烨 杨洁 石芸 杨慧欣 PAN Ningjing;ZHU Ye;YANG Jie;SHI Yun;YANG Huixin(Gempharmatech Co.,Ltd.,Changzhou Branch,Changzhou 213000,China)
机构地区:[1]江苏集萃药康生物科技股份有限公司常州分公司,常州213000
出 处:《实验动物科学》2024年第2期46-50,共5页Laboratory Animal Science
基 金:江苏省实验动物协会科研课题(DWXH202213)。
摘 要:目的探究三种筑巢材料及放置量对小鼠筑巢与繁育性能的影响。方法C57BL/6JGpt(B6)小鼠、BALB/c Nj-Foxn1nu/Gpt(BALB/c-nu)小鼠随机各分为12组,每组36只(雄雌1∶2配繁),分别添加2、4、6、8 g 4种克重的拉菲草、纸棉、擦手纸筑巢材料,合笼后一周进行筑巢评分,每周统计总活产仔数、总离乳数、小鼠离乳体质量,持续统计5个月。结果(1)两种品系小鼠拉菲草组、擦手纸组筑巢评分均显著优于纸棉组(P<0.05),筑巢评分与筑巢材料放置量无显著关联(P>0.05)。(2)两种品系小鼠总活产仔数、总离乳数与筑巢材料种类均无显著关联(P>0.05);B6小鼠6 g擦手纸组总活产仔数、总离乳数显著优于2 g擦手纸组(P<0.05);BALB/c-nu小鼠2 g擦手纸组总活产仔数显著优于6 g擦手纸组(P<0.05),2 g筑巢材料组总离乳数均显著优于8 g筑巢材料组(P<0.05);两种品系小鼠离乳体质量与筑巢材料种类、放置量均无显著关联(P>0.05)。结论两种品系对不同筑巢材料及放置量存在差异。Objective To investigate the effects of three nesting materials and placement levels on the nesting and breeding performance of mice.Method C57BL/6JGpt(B6)mice and BALB/cNj-Foxn1nu/Gpt(BALB/c-nu)mice were randomly divided into 12 groups(n=36,trio-bred).Mice were provided with three kinds of nesting materials(raffia,paper cotton and paper tissue)and four placements(2 g,4 g,6 g and 8 g)levels respectively.Nesting scores were assigned on the first week after mating,and total litter size,total weaning pups and weaning weight of pups were counted weekly for 5 months.Result(1)The nesting scores of the raffia and paper tissue groups were significantly better than those of the paper cotton group in both strains(P<0.05),and there was no significant correlation between nesting scores and the placement level of nesting material(P>0.05).(2)There was no significant correlation between total litter size,total weaning pups and the kinds of nesting material in both strains(P>0.05);the total litter size and total weaning pups in the 6 g paper tissue group of B6 strain was significantly better than that in the 2 g paper tissue group(P<0.05);the total litter size in the 2 g paper tissue group was significantly better than that in the 6 g paper tissue group(P<0.05),and total weaning pups in the 2 g nesting material groups were significantly better than that in the 8 g nesting material groups(P<0.05);there was no significant correlation between weaning weight of pups and types and placement levels of nesting material in both two strains.Conclusion There were differences between the two strains for types and placement levels of nesting materials.
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