空气和纯氧复苏方案在新生儿窒息中的应用价值比较  

Comparison of the application value of air and pure oxygen resuscitation programs in neonatal asphyxia

作　　者：王先言 陈晓敏 张东梅[1] WANG Xianyan;CHEN Xiaomin;ZHANG Dongmei(Neonatal Intensive Care Unit,the First People's Hospital of Shangqiu,Shangqiu 476100,China)

机构地区：[1]商丘市第一人民医院新生儿重症监护室,河南商丘476100

出　　处：《临床医学研究与实践》2024年第14期120-123,共4页Clinical Research and Practice

摘　　要：目的分析空气和纯氧复苏方案在新生儿窒息中的应用价值。方法将我院2021年1月至2022年6月收治的60例窒息新生儿作为研究对象,以复苏方案将其分为空气组(30例,空气复苏方案)和纯氧组(30例,纯氧复苏方案)。比较两种复苏方案的应用价值。结果出生5、10、15 min时,空气组的Apgar评分显著高于纯氧组(P<0.05)。两组娩出5 min时的心率比较,差异无统计学意义(P>0.05);空气组的自主呼吸建立时间、首次啼哭时间显著短于纯氧组,差异具有统计学意义(P<0.05)。治疗后,空气组的动力参数(PI)显著高于纯氧组,阻力参数(RI)、收缩期血液流速最高值/舒张晚期血液流速最高值(S/D)显著低于纯氧组,差异具有统计学意义(P<0.05)。治疗后,空气组的动脉血氧分压(PaO_(2))、血氧饱和度(SaO_(2))显著高于纯氧组,动脉血二氧化碳分压(PaCO_(2))、高迁移率族蛋白B-1(HMGB-1)及可溶性髓系细胞触发受体-1(sTREM-1)显著低于纯氧组,差异具有统计学意义(P<0.05)。结论在新生儿窒息的复苏方案中,空气复苏相较纯氧复苏具有更佳的应用价值,倡导临床应用。Objective To analyze the application value of air and pure oxygen resuscitation in neonatal asphyxia.Methods Sixty asphyxiated neonates admitted in our hospital from January 2021 to June 2022 were enrolled in the study.The neonates were divided into air group(30 cases,air resuscitation program)and pure oxygen group(30 cases,pure oxygen resuscitation program)by resuscitation program.The application value of two resuscitation programs were compared.Results At 5,10 and 15 min after birth,the Apgar score of the air group was significantly higher than that of the pure oxygen group(P<0.05).There was no significant difference in heart rate at 5 min after delivery between the two groups(P>0.05);the establishment time of spontaneous breathing and the first crying time in the air group were significantly shorter than those in the pure oxygen group,and the differences were statistically significant(P<0.05).After treatment,the pulsatility index(PI)of the air group was significantly higher than that of the pure oxygen group,and the resistance index(RI)and systolic blood pressure/diastolic blood pressure(S/D)were significantly lower than those of the pure oxygen group,and the differences were statistically significant(P<0.05).After treatment,the arterial partial pressure of oxygen(PaO_(2))and oxygen saturation of blood(SaO_(2))in the air group were significantly higher than those in the pure oxygen group,and the arterial partial pressure of carbon dioxide(PaCO_(2)),human high mobility group box-1(HMGB-1)and soluble triggering receptor expresseson myeloid cells-1(sTREM-1)were significantly lower than those in the pure oxygen group,and the differences were statistically significant(P<0.05).Conclusion In the resuscitation program of neonatal asphyxia,air resuscitation has better application value than pure oxygen resuscitation,and clinical application is advocated.

关 键 词：新生儿窒息 空气复苏 纯氧复苏 

分 类 号：R722.12[医药卫生—儿科]