芦荟的化学成分研究  

Studies on the chemical constituents of Aloe vera

作　　者：余榕 林志达 何健民 YU Rong;LIN Zhi-da;HE Jian-minn(Technology Center,Gongbei Customs,Zhuhai 519075,China;School of Resource and Environment,Baoshan University,Baoshan 678000,China)

机构地区：[1]拱北海关技术中心,广东珠海5519075 [2]保山学院资源环境学院,云南保山678000

出　　处：《化学研究与应用》2024年第5期1101-1106,共6页Chemical Research and Application

基　　金：云南省地方本科高校基础研究联合专项项目(2018FH001-126)资助;云南省2018年高校本科教育教学改革研究项目(JG2018225)资助。

摘　　要：采用硅胶、Sephadex LH-20凝胶柱色谱方法等对阿福花科(Asphodelaceae)植物芦荟Aloe vera(L.)Burm.f.的化学成分进行分离纯化,并通过核磁共振波谱学技术对所分离化合物进行结构鉴定。从芦荟中分离鉴定了12个化合物,包括3个色原酮:5-(S-2’-oxo-4’-hydroxypentyl)-2-hydroxymethylchromone(1)、5-(4E-2’-oxopentenyl)-2-hydroxymethylchromone(2)、5-(2-oxopentyl)-2-hydroxymethylchromone(3),1个酚酸:咖啡酸(4),6个蒽醌:大黄素(5)、大黄酚(6)、芦荟大黄素(7)、大黄素-8-β-D-吡喃葡萄糖苷(8)、芦荟苷A和B(9和10),1个香豆素:好望角芦荟内酯(11)和1个氧杂苯并吡喃类成分:8-hydroxy-2-(2-hydroxypropyl)-7-acetyl-1-oxaphenalene(12)。其中,咖啡酸(4)和氧杂苯并吡喃类成分(12)首次从芦荟属植物中发现。Silica gel column chromatography and Sephadex LH-20 column chromatography were applied to separate and purify the compounds from the Aloe vera(L.)Burm.f.(Asphodelaceae).Nuclear magnetic resonance spectroscopy was adopted to identify the structures of the isolated compounds.Twelve compounds were isolated and identified,including three chromones,5-(S-2'-oxo-4'-hydroxypentyl)-2-hydroxymethylchromone(1),5-(4E-2'-oxo-pentenyl)-2-hydroxymethylchromone(2),and 5-(2-oxopentyl)-2-hydroxymethylchromone(3);one phenolic acid,caffeic acid(4);six anthraquinones,emodin(5),chrysophanol(6),aloe-emodin(7),emodin-8-β-D-glucopyranoside(8),aloins A and B(9 and 10);one coumarin feralolide(11),and one oxaphenalene compound 8-hydroxy-2-(2-hydroxypropyl)-7-acetyl-1-oxaphenalene(12).Among them,compounds 4 and 12 were isolated from this genus for the first time.

关 键 词：芦荟 阿福花科 色原酮 蒽醌 氧杂苯并吡喃 

分 类 号：O629[理学—有机化学]