1059名济南市育龄男性体育锻炼情况与精液质量的相关分析  

Correlation between physical exercise and semen quality in 1059 men of childbearing age in Jinan City

作　　者：王文钰 柳松 仕治达 杨慧军 任静朝 金会东 张光辉[4] 周紫垣[4] 杨光红[1] WANG Wenyu;LIU Song;SHI Zhida;YANG Huijun;REN Jingchao;JIN Huidong;ZHANG Guanghui;ZHOU Ziyuan;YANG Guanghong(School of Public Health,Guizhou Medical University,Guiyang,Guizhou Province,550025;Reproductive Medicine Center,Shandong Maternal and Child Health Hospital,Jinan,Shandong Province,250014;School of Public Health,Chongqing Medical University,Chongqing,400016;Department of Environmental Health,Faculty of Military Preventive Medicine,Army Medical University(Third Military Medical University),Chongqing,400038,China)

机构地区：[1]贵州医科大学公共卫生与健康学院,贵州贵阳550025 [2]山东省妇幼保健院生殖医学中心,山东济南250014 [3]重庆医科大学公共卫生学院,重庆400016 [4]陆军军医大学(第三军医大学)军事预防医学系环境卫生学教研室,重庆400038

出　　处：《陆军军医大学学报》2024年第10期1164-1171,共8页Journal of Army Medical University

基　　金：科技部重大研发专项(2018YFC1004201);国家自然科学基金面上项目(82273663);国家自然科学基金青年项目(82003489)。

摘　　要：目的探究体育锻炼对精液质量的影响,为男性生殖健康的提高提供基础数据及理论依据。方法采用横断面研究方法,以到山东省妇幼保健院生殖中心就诊和体检的1059名男性作为研究对象,采用问卷调查人口学资料和体育锻炼等资料。采用计算机辅助分析技术分析精子总数、精子浓度、总精子活动率、前向运动以及精子正常形态百分率,采用Logistic回归模型和多重线性回归模型分析体育锻炼对精液质量的影响。结果校正年龄、体质量指数、饮酒和吸烟等混杂因素后,Logistic回归分析发现:体育锻炼强度为中等和大强度持久者精液质量异常的发生风险增高(OR值分别为2.103和2.229);与每次体育活动时间10 min以下相比,每次体育活动时间为20 min以上者精液质量异常的发生风险降低(体育活动>20~30 min、>30~60 min、>60 min者的OR值分别为0.357、0.256和0.289);体育活动频率与精液质量异常与否之间差异无统计学意义(P>0.05)。锻炼情况较好者精液质量异常的发生风险低,OR值为0.711。多重线性回归分析发现:体育活动频率(β=7.474,95%CI:4.800~10.149)是精子浓度的影响因素(P<0.05);每次体育活动时间(β=20.632,95%CI:7.634~33.629)是精子总数的影响因素(P<0.05);体育锻炼强度(β=-1.461,95%CI:-2.392,-0.530)和每次体育活动时间(β=2.608,95%CI:1.404,3.812)是前向运动精子百分率的影响因素(P<0.05);体育锻炼强度(β=-1.934,95%CI:-3.238~-0.630)、每次体育活动时间(β=4.211,95%CI:2.525~5.897)和体育活动频率(β=-2.008,95%CI:-3.480~-0.536)是精子总活动率的影响因素(P<0.05)。结论体育锻炼可能影响精液质量,较大强度的体育锻炼可能是精液质量异常的危险因素,较长体育运动时间可能提高精液质量。适当的体育锻炼情况有助于提高精液质量。Objective To explore the effect of physical exercise on semen quality in order to provide basic data and theoretical basis for the improvement of male reproductive health.Methods A cross-sectional study was conducted on 1059 males who visited the Reproductive Medicine Center of Shandong Maternal and Child Health Hospital for medical treatment and physical examination during July 2022 and April 2023.Their demographic data and physical exercise data were surveyed with questionnaires.Total sperm count,sperm concentration,total sperm motility,forward movement and normal sperm morphology were analyzed with computer aided analysis.Logistic regression model and multiple linear regression model were applied to analyze the effects of physical exercise on semen quality.Results After adjustment for confounding factors such as age,body mass index,alcohol consumption and smoking,logistic regression analysis showed that the risk of abnormal semen quality was increased in patients with moderate and heavy exercise intensity(OR=2.103,OR=2.229).Compared with the participants with physical exercise≤10 min per session,those with>20 min per session had a lower risk of abnormal semen quality(OR=0.357,0.256,0.289 for exercise time for>20~30,>30~60,>60 min,respectively).There was no statistical significance between physical exercise frequency and semen quality(P>0.05).The participants having exercise well were at a lower risk for abnormal semen quality(OR=0.711).Multiple linear regression analysis revealed that the frequency of physical exercise was an influencing factor of sperm concentration(β=7.474,95%CI:4.800~10.149,P<0.05);the time of physical exercise per session was an influencing factor for total sperm count(β=20.632,95%CI:7.634~33.629);the intensity of physical exercise(β=-1.461,95%CI:-2.392~-0.530)and time of physical exercise per session(β=2.608,95%CI:1.404~3.812,P<0.05)were influencing factors for percentage of forward motility sperm(P<0.05);and physical exercise intensity(β=-1.934,95%CI:-3.238~-0.630),time of physica

关 键 词：体育锻炼 精液质量 流行病学研究 影响因素 

分 类 号：G804.2[文化科学—运动人体科学] R195.2[文化科学—体育学] R339.21[医药卫生—卫生统计学]