不同性别人群体质指数和腰围对高血压发病影响的前瞻性研究  

Prospective study on impact of body mass index(BMI)and waist circumference on hypertension in different sex population

作　　者：巴合古·依明尼亚孜 马润泽 迪丽胡玛尔·艾力 乔婷婷 罗涛 戴江红[1] Bahegu Yimingniyazi;MA Runze;Dilihumaer Aili;QIAO Tingting;LUO Tao;DAI Jianghong(School of Public Health,Xinjiang Medical University,Urumqi 830017,China;School of Nursing,Xinjiang Medical University,Urumqi 830017,China)

机构地区：[1]新疆医科大学公共卫生学院,乌鲁木齐830017 [2]新疆医科大学护理学院,乌鲁木齐830017

出　　处：《新疆医科大学学报》2024年第5期621-627,632,共8页Journal of Xinjiang Medical University

基　　金：国家自然科学基金项目(82360662,82160640);科技创新团队“天山创新团队”项目(2022TSYCTD0013)。

摘　　要：目的 分析不同性别人群体质指数(BMI)和腰围与高血压发病风险的关联。方法 以“新疆多民族自然人群队列建设及健康随访研究”和田调查现场的农村居民作为研究对象,2018年作为基线调查,随访至2022年的高血压的发病情况。在不同性别人群中,根据其基线BMI和腰围进行联合分组,采用多因素Logistic回归模型分析不同BMI和腰围联合分组与高血压发病的关系。结果 纳入分析者7 010例,其中男性2 654例,女性4 356例。4年随访期间,总人群高血压标化累积发病率为25.16%,男性高血压标化累积发病率为23.79%,女性高血压标化累积发病率为26.74%。调整相关混杂因素后,男性仅BMI超标组、仅腰围超标组、BMI及腰围均超标组高血压的发病风险分别为BMI及腰围均正常组的1.733倍(95%CI:1.211~2.479)、1.675倍(95%CI:1.184~2.370)、2.249倍(95%CI:1.808~2.797);女性仅腰围超标组、BMI及腰围均超标组高血压的发病风险分别为BMI及腰围均正常组的1.506倍(95%CI:1.185~1.914)、1.887倍(95%CI:1.559~2.283),而仅BMI超标组与BMI及腰围均正常组比较差异无统计学意义;敏感性分析显示,BMI和腰围对高血压的影响存在性别差异。结论 不同性别人群BMI和腰围超标均是高血压发病的危险因素,联合使用BMI和腰围可以更好地识别高血压的发病风险;BMI和腰围对高血压的影响存在性别差异,男性仅BMI超标者高血压的发病风险高于仅腰围超标者;女性仅腰围超标者高血压的发病风险高于仅BMI超标者。Objective To analyze the association between body mass index(BMI)and waist circumference and the risk of hypertension in different sex population.Methods Residents at Hotan survey site in“Xinjiang multi-ethnic cohort”were used as research subjects.2018 was used as baseline survey,and the incidence of hypertension was followed up to 2022.Among people of different genders,they were jointly grouped according to their baseline BMI and waist circumference,and a multi-factor Logistic regression model was used to analyze the relationship between different joint groups of BMI and waist circumference and the incidence of hypertension.Results 7010 cases were included in the analysis,including 2654 males and 4356 females.During the 4-year follow-up period,the total population standardized cumulative incidence of hypertension was 25.16%,the male standardized cumulative incidence of hypertension was 23.79%,and the female standardized cumulative incidence of hypertension was 26.74%.After adjusting for related confounding factors,in men,the incidence risk of hypertension in the only BMI excessive group,only waist circumference excessive group,and both BMI and waist circumference excessive group was 1.733 times(95%CI:1.211~2.479),1.675 times(95%CI:1.184~2.370)and 2.249 times(95%CI:1.808~2.797)than that in normal BMI and waist circumference group,respectively;in women,the incidence risk of hypertension in the only waist circumference excessive group,and both BMI and waist circumference excessive group was 1.506 times(95%CI:1.185~1.914)and 1.887 times(95%CI:1.559~2.283)than that in the normal BMI and waist circumference group,respectively,but there was not statistically significant difference between only BMI excessive group and normal BMI and waist circumference group.Sensitivity analysis revealed sex differences in the effect of BMI and waist circumference on hypertension.Conclusion Both BMI and waist circumference excessive are both risk factors for hypertension in different genders.Combined use of BMI and waist circumferen

关 键 词：性别 体质指数 腰围 高血压 前瞻性研究 

分 类 号：R544.1[医药卫生—心血管疾病]