神经内镜治疗基底节脑出血患者的效果及其对认知功能的影响  

Effect of Neuroendoscopy on Basal Ganglia Hemorrhage and Its Influence on Cognitive Function

作　　者：刘鹏 邓中坤 LIU Peng;DENG Zhongkun(Department of Neurosurgery,Xiushan County People's Hospital,Xiushan,Chongqing,409900 China)

机构地区：[1]秀山县人民医院神经外科,重庆秀山409900

出　　处：《中外医疗》2024年第9期47-50,共4页China & Foreign Medical Treatment

摘　　要：目的探究神经内镜对基底节脑出血患者的治疗效果及其对认知功能的影响。方法随机选取2021年12月—2023年12月秀山县人民医院收治的70例基底节脑出血患者作为研究对象,利用最新统计学软件生成随机序列后予以分为对照组、观察组,各35例。对照组予以显微手术治疗,观察组予以神经内镜下血肿清除术治疗。对比两组治疗效果、血清学指标、认知功能及不良事件发生情况。结果观察组治疗总有效率高于对照组,差异有统计学意义(χ^(2)=3.968,P<0.05)。观察组C-反应蛋白(C-reactive Protein,CRP)、血浆内皮素(Endothelin,ET)、白细胞介素-6(Interleukin-6,IL-6)水平均低于对照组,差异有统计学意义(t=22.851、6.318、13.663,P均<0.05);观察组认知功能评定量表(Montreal Cognitive Assessment,MoCA)中的注意力、延迟记忆、抽象思维、语言流畅度评分均高于对照组,差异有统计学意义(t=5.599、4.437、2.406、2.231,P均<0.05)。观察组不良事件总发生率低于对照组,差异有统计学意义(χ^(2)=5.080,P<0.05)。结论在基底节脑出血患者的手术选择上,神经内镜治疗效果突出,有利于改善患者的血清学指标水平和认知功能,且不良事件发生情况较低。Objective To explore the effect of neuroendoscopy on patients with basal ganglia hemorrhage and its influ⁃ence on cognitive function.Methods 70 patients with basal ganglia cerebral hemorrhage admitted to Xiushan County People's Hospital from December 2021 to December 2023 were randomly selected as the research subjects,and were divided into control group and observation group using the latest statistical software to generate random sequences,with 35 patients in each group.The control group was treated with microsurgery,and the observation group was treated with neuroendoscopic hematoma removal.The therapeutic effect,serological indexes,cognitive function and adverse events were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(χ^(2)=3.968,P<0.05).The levels of Creactive protein(CRP),plasma endothelin(ET)and interleukin-6(IL-6)in the observation group were lower than those in the control group,and the differences were statistically significant(t=22.851,6.318,13.663,all P<0.05).The scores of attention,delayed memory,abstract thinking and language fluency in Montreal Cognitive Assessment(MoCA)in the observation group were higher than those in the control group,and the differences were statistically significant(t=5.599,4.437,2.406,2.231,all P<0.05).The total incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant(χ^(2)=5.080,P<0.05).Conclusion In the surgical selection of patients with basal ganglia cerebral hemorrhage,neuroendoscopy has a prominent effect,which is conducive to improving the serological index level and cognitive function of patients,and the incidence of adverse events is relatively low.

关 键 词：基底节脑出血 神经内镜 治疗效果 血清学指标 认知功能 不良事件 

分 类 号：R4[医药卫生—临床医学]