不同胰岛素给药方式对妊娠糖尿病患者血糖及妊娠结局的影响  

Effects of Different Insulin Administration Modes on Blood Glucose and Pregnancy Outcomes in Patients with Gestational diabetes

作　　者：卜宝凤 林秀盏 卜宝玲 BU Baofeng;LIN Xiuzhan;BU Baoing(Jinjiang Hospital(Shanghai Sixth Hospital Fujian Hospital),Quanzhou,Fujian Province,362200 China;Quanzhou Women's and Children's Hospital,Quanzhou,Fujian Province,362000 China;The Second Affiliated Hospital of Fu-jian Medical University,Quanzhou,Fujian Province,362000 China)

机构地区：[1]福建省晋江市医院(上海六院福建医院),福建泉州362200 [2]泉州市妇幼保健院·儿童医院,福建泉州362000 [3]福建医科大学附属第二医院,福建泉州362000

出　　处：《糖尿病新世界》2024年第5期73-76,共4页Diabetes New World Magazine

摘　　要：目的探究妊娠糖尿病患者接受不同胰岛素给药方式的效果。方法回顾性选取2022年10月—2023年9月于福建省晋江市医院(上海六院福建医院)就诊的90例妊娠糖尿病患者的临床资料,按照给药方式分为对照组(n=45,胰岛素皮下注射)、观察组(n=45,胰岛素泵持续注射),比较两组患者血糖控制效果及母婴结局。结果治疗后,两组血糖水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P均<0.05)。相较于对照组,观察组不良妊娠结局总发生率、新生儿不良结局总发生率均更低,差异有统计学意义(P均<0.05)。结论妊娠糖尿病患者应用胰岛素泵持续注射治疗,血糖水平控制效果更佳,患者及新生儿不良结局发生风险均更低。Objective To explore the effect of different insulin administration methods in gestational diabetes patients.Methods Clinical data of 90 patients with gestational diabetes treated in Jinjiang Hospital of Fujian Province(Shang-hai Sixth Hospital Fujian Hospital)from October 2022 to September 2023 were retrospectively selected,and divided into control group(n=45,subcutaneous insulin injection)and observation group(n=45,continuous insulin pump injec-tion)according to the way of administration.The blood glucose control effect and maternal and infant outcomes were compared between the two groups.Results After treatment,the blood glucose level of both groups was lower than be-fore treatment,and the observation group was lower than the control group,the differences were statistically significant(both P<0.05).Compared with the control group,the total incidence of adverse pregnancy outcomes and total neonatal adverse outcomes in the observation group were lower,and the differences were statistically significant(both P<0.05).Conclusion Patients with gestational diabetes mellitus treated with continuous injection of insulin pump have better glycemic level control and lower risk of adverse outcomes in both patients and newborns.

关 键 词：妊娠糖尿病 产妇 胰岛素皮下注射 胰岛素泵持续注射 血糖水平 母婴结局 

分 类 号：R587.1[医药卫生—内分泌]