DNA水凝胶的构建及柔性电子应用  

Construction of DNA Hydrogels and Flexible Electronic Applications

作　　者：李颀 王丽华[1,3] 樊春海 叶德楷 Qi Li;Li-hua Wang;Chun-hai Fan;De-kai Ye(CAS Key Laboratory of Interfacial Physics and Technology,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800;University of Chinese Academy of Sciences,Beijing 100049;Zhangjiang Laboratory,Shanghai 201210;School of Chemistry and Chemical Engineering,Shanghai Jiao Tong University,Shanghai 200240)

机构地区：[1]中国科学院上海应用物理研究所、中国科学院界面物理与技术重点实验室,上海201800 [2]中国科学院大学,北京100049 [3]张江实验室,上海201210 [4]上海交通大学化学化工学院,上海200240

出　　处：《高分子学报》2024年第6期655-672,共18页Acta Polymerica Sinica

基　　金：上海市启明星(项目号22QA1411800)资助项目

摘　　要：水凝胶材料能有效提升柔性电子器件与人体组织的相容性,在智能穿戴、健康监测和人机接口等研究领域展现了巨大的应用潜力.然而,传统的水凝胶材料难以在器件界面进行原位无损的结构调控,同时也缺乏对多类型生化刺激的识别响应能力,这制约了水凝胶柔性电子器件的高性能构筑和多功能应用. DNA水凝胶制备工艺温和,结构精确可控且具有丰富的生化识别响应性,是柔性电子器件功能化的理想材料之一.本文着重介绍了DNA水凝胶的材料特性及其柔性电子器件应用的研究进展.首先介绍了纯DNA水凝胶和杂化DNA水凝胶的制备方法,以及面向多类型功能界面的构筑策略.通过对DNA水凝胶力学特性、识别响应性和生物相容性的深入分析,展示了其在器件功能调控和生物医学应用方面的重要价值.其次,详细探讨了DNA水凝胶功能化的柔性电子器件在传感、储能和显示等方面的研究进展,展现了其在人体健康监测和智能穿戴领域的应用前景.最后,对DNA水凝胶在柔性生物电子领域的未来发展进行了展望.Hydrogels serve as effective functional interface materials that enhance compatibility between human tissues and flexible electronic devices.These hydrogel-based devices exhibit great potential in research areas like smart wearables,health monitoring,and human-machine interfaces.However,traditional hydrogel materials pose challenges in achieving controllable fabrication at the device interface and designing responses to biological and chemical stimuli.These limitations restrain the creation of high-performance hydrogel-based flexible electronic devices for intelligent applications.This article primarily aims to introduce the distinctive material properties of novel DNA hydrogels and their advancements in flexible electronic devices.Initially,we introduced the fabrication techniques for both pure and hybrid DNA hydrogels,alongside strategies for regulating functional interfaces.Subsequently,an in-depth analysis of DNA hydrogels'mechanical properties,stimulus responsiveness,and biocompatibility is provided.Specifically,we explored how these crucial attributes can be harnessed in designing functional devices and biomedical applications.Moreover,we outlined the progress of DNA hydrogel-based flexible electronic devices in sensing,energy storage,and displaying.These advancements showcase their significant potential in human health monitoring and smart wearables.Finally,we discussed the prospective development directions of DNA hydrogels in the domain of flexible bioelectronics.

关 键 词：DNA水凝胶 刺激响应 柔性电子器件 传感器 

分 类 号：TQ427.26[化学工程]