民族药文王一支笔不同药用部位止血作用的筛选研究  

Researches on Hemostatic Effect of Different Medicinal Parts of Balanophora involucrata

作　　者：殷莉 程刚 瞿涛[2] 顾秀峰 陈桂林[3] 吴云毅 YIN Li;CHENG Gang;QU Tao;GU Xiufeng;CHEN Guilin;WU Yunyi(Shiyan Hospital of Integrated Traditional and Western Medicine,Shiyan 442001,China;Hubei University of Chinese Medicine,Wuhan 430065,China;Wuhan Botanical Garden,Chinese Academy of Sciences,Wuhan 430074,China)

机构地区：[1]湖北省十堰市中西医结合医院,湖北十堰442001 [2]湖北中医药大学,湖北武汉430065 [3]中国科学院武汉植物园,湖北武汉430074

出　　处：《中国民族民间医药》2024年第8期33-36,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：湖北省卫健委中医药科研青年人才项目(ZY2021Q035)。

摘　　要：目的:探讨文王一支笔不同药用部位(花序、花茎、根茎)水煎液的止血作用。方法:将实验动物随机分为空白对照组,云南白药组,文王一支笔根茎、花茎、花序三个不同部位给药组(每个部位再分为高、低剂量组),连续给药5d后,采用断尾法测定小鼠出血时间,毛细管法测定小鼠凝血时间,且测定大鼠血浆复钙时间。结果:与空白组比较,云南白药组、文王一支笔花序和花茎高低剂量组出血时间、凝血时间与血浆复钙时间均明显缩短(P<0.05或P<0.01);文王一支笔根茎的作用不显著。结论:文王一支笔花序和花茎水煎液均有较好的止血、促凝血作用,根茎的作用次之。Objective To explore the hemostatic effect of aqueous extract of different medicinal parts(inflorescence,scape,and rhizome) from Balanophora involucrata.Methods The experimental animals were randomly divided into blank control group,Yunnan Baiyao group,Balanophora involucrata's inflorescence,scape,and rhizome groups(each part was divided into high and low dose groups).After continuous administration for 5 days,the hemostasis time(BT) and clotting time(CT) of mice were measured by tail-cutting method and capillary tube method.The plasma recalcification time(PRT) were examined on Wistar rats.Results Compared with the blank group,Yunnan Baiyao group,aqueous extracts of Balanophora involucrata's inflorescence and scape groups significantly shortened the BT,CT and PRT(P<0.05 or P<0.01),while the rhizome of Balanophora involucrata exhibited no obvious hemostatic effect.Conclusion Among different medicinal parts of Balanophora involucrata,inflorescence and scape showed the strong promotion on hemostasis and coagulation,while the effect of rhizome was weaker.

关 键 词：文王一支笔 花序 花茎 根茎 止血作用 

分 类 号：R285.5[医药卫生—中药学]