基于激光加工的医疗器械功能性表面研究现状  

Functional surfaces of medical devices based on laser processing:a review

作　　者：杜鑫豪 刘志华 张智雷 杜策之 隋建波 王成勇[1] DU Xinhao;LIU Zhihua;ZHANG Zhilei;DU cezhi;SUI Jianbo;WANG Chengyong(College of Mechanical and Electrical Engineering,Guangdong University of Technology,Guangzhou 510000,China)

机构地区：[1]广东工业大学机电工程学院,广州510000

出　　处：《金刚石与磨料磨具工程》2024年第2期206-220,共15页Diamond & Abrasives Engineering

基　　金：国家自然科学基金重点项目(51735003);国家自然科学基金面上项目(52175386);佛山市重点领域科技攻关项目(2020001006106)。

摘　　要：制备功能性表面是提升医疗器械治疗性能和安全性的重要方法之一。当前,基于激光加工的功能性表面微纳结构制造技术在优化医疗器械表面性能方面应用广泛。综述了医疗植入器械和手术器械表面激光加工功能性微纳结构在细胞功能调控、抗菌性、耐蚀性、摩擦特性、抗黏附性等方面的研究现状,剖析了当前医疗器械功能性表面激光加工的优势和局限,展望了医疗器械功能性表面激光加工技术的发展前景。The preparation of functional surfaces is one of the important methods to enhance the therapeutic performance and safety of medical devices.Currently,the fabrication of functional surface microstructures based on laser processing is widely used in the optimizing medical device surface properties.This paper reviews the current research status of functional microstructures for laser processing of medical implantable and surgical devices in terms of cell function regulation,antimicrobial properties,corrosion resistance,frictional properties,and anti-adhesion,etc.It analyzes the advantages and limitations of laser processing of functional surfaces for medical devices and outlines the development prospects of laser processing technology for functional surfaces for medical devices.

关 键 词：激光加工 微纳结构 功能性表面 植入器械 手术器械 

分 类 号：TH122[机械工程—机械设计及理论] R197.39[医药卫生—卫生事业管理] V261.8[医药卫生—公共卫生与预防医学] TG665[航空宇航科学与技术—航空宇航制造工程]