低分子量肝素钙联合寿胎丸加减方治疗早期先兆流产合并绒毛膜下血肿的临床研究  

Clinical study of low molecular weight heparin calcium combined with Shoutai pill plus or minus prescription in the treatment of early threatened abortion complicated with subchorionic hematoma

作　　者：方芳[1] 陈晓勇[1] FANG Fang;CHEN Xiaoyong(Jiangxi Maternal and Child Health Hospital/Jiangxi Key Lab of Female Reproduction of Integrated Traditional Chinese and Western Medicine,Nanchang 330006,China)

机构地区：[1]江西省妇幼保健院中医科/江西省中西医结合女性生殖重点研究室,南昌330006

出　　处：《上海医药》2024年第9期29-32,36,共5页Shanghai Medical & Pharmaceutical Journal

基　　金：国家中医药管理局第七批名老中医药专家学术经验继承工作项目;中国妇幼保健协会-华润三九中医中西医结合妇幼健康专项研究基金(ZXY2020B04)。

摘　　要：目的:探讨低分子量肝素钙联合寿胎丸加减方治疗早期先兆流产合并绒毛膜下血肿(SCH)的临床疗效及其作用机制。方法:将早期先兆流产合并SCH患者60例随机分为对照组和治疗组,各30例。对照组采用寿胎丸加减方治疗,治疗组在对照组的基础上加用低分子量肝素钙治疗。比较两组治疗效果、症状缓解时间、血清指标以及药物安全性。结果:治疗组总有效率高于对照组,各项症状缓解时间短于对照组;血清指标改善情况优于对照组(P<0.05)。两组均未出现明显不良反应。结论:联合疗法效果确切,能够快速缓解患者症状,改善血清指标水平,且安全性较高。Objective:To investigate the clinical efficacy and mechanism of low molecular weight heparin calcium combined with Shoutai pill plus or minus prescription in the treatment of early threatened abortion complicated with subchorionic hematoma(SCH).Methods:Sixty cases of the patients were randomly divided into a control group and a treatment group with 30 cases each.Both groups were first treated with Shoutai pill plus or minus prescription and then low molecular weight heparin calcium was additionally given in the treatment group.The therapeutic effect,the time for symptom remission,the serum indexes and drug safety were compared between the two groups.Results:The total effective rate was higher,the time for symptoms remission was shorter,and the improvement of serum indexes was better in the treatment group than the control group(P<0.05).There were no obvious adverse reactions in the two groups.Conclusion:Combination therapy has a definite effect and a high safety profile,can quickly relieve patients’symptoms and improve serum index levels.

关 键 词：早期先兆流产 绒毛膜下血肿 低分子量肝素钙 寿胎丸加减方 

分 类 号：R973.2[医药卫生—药品] R714.21[医药卫生—药学]