鼻咽癌早期诊断研究进展和意义  

Research Progress and Significance in Early Diagnosis of Nasopharyngeal Carcinoma

作　　者：刘其洪 范小琴 王志强 李清明 聂国辉[2] LIU Qihong;FAN Xiaoqin;WANG Zhiqiang;LI Qingming;NIE Guohui(Department of Otolarynology,Sun Yat-sen University Eighth Affiliated Hospital,Shenzhen 518000,China;Department of Otolarynology,Shenzhen Second People's Hospital,Shenzhen 518000,China)

机构地区：[1]中山大学附属第八医院(深圳福田)耳鼻喉科,广东深圳518000 [2]深圳市第二人民医院耳鼻喉科,广东深圳518000

出　　处：《医学综述》2024年第12期1429-1436,共8页Medical Recapitulate

基　　金：深圳市福田区卫生公益性科研项目(FTWS2021088)。

摘　　要：鼻咽癌是头颈部最常见的恶性肿瘤之一,具有地域性,我国南方地区高发,远高于世界平均水平。早期的鼻咽癌患者预后较好,而晚期患者放疗预后欠佳,容易复发转移,5年生存率低。虽然近年来鼻咽癌的诊断和治疗水平有了明显提高,但死亡率仍较高,尤其是晚期患者。因此,早期诊断对于改善鼻咽癌患者预后尤为关键,目前鼻咽癌早期诊断的手段主要有EB病毒血清标志物、影像学检查、内镜检查等,而基因检测、拉曼光谱等新技术也为鼻咽癌的早期筛查提供了选择。Nasopharyngeal carcinoma is one of the most common malignant tumors of head and neck,with regional characteristics.It is highly prevalent in southern China,far exceeding the world average.Early nasopharyngeal carcinoma patients have a good prognosis,while the late stage patients have poor radiotherapeutic prognosis,are prone to recurrence and metastasis,and have a low 5-year survival rate.Although the diagnosis and treatment level of nasopharyngeal carcinoma has significantly improved in recent years,the mortality rate is still high,especially for advanced patients.Therefore,early diagnosis is particularly crucial for improving the prognosis of the patients.Currently,the main methods for early diagnosis of nasopharyngeal carcinoma include EB virus serum markers,imaging examinations,endoscopic examinations,etc.,while new technologies such as genetic testing and Raman spectroscopy also provide choices for the early screening of nasopharyngeal carcinoma.

关 键 词：鼻咽癌 早期诊断 肿瘤细胞 

分 类 号：R766.3[医药卫生—耳鼻咽喉科]