多西环素联合皮肤修护无菌敷料治疗玫瑰痤疮的临床效果  

Clinical Effect of Doxycycline Combined with Skin Repair Sterile Dressings in Treatment of Acne Rosacea

作　　者：郑斯文 Zheng Siwen(Department of Dermatology,The Third Affiliated Hospital of Jinzhou Medical University,Jinzhou 121000,Liaoning Province,)

机构地区：[1]锦州医科大学附属第三医院皮肤科,辽宁锦州121000

出　　处：《中国社区医师》2024年第10期26-28,共3页Chinese Community Doctors

摘　　要：目的:探讨多西环素联合皮肤修护无菌敷料治疗玫瑰痤疮的临床效果。方法:选取2019年8月—2021年8月锦州医科大学附属第三医院皮肤科收治的玫瑰痤疮患者78例作为研究对象,随机分为两组,各39例。对照组给予多西环素治疗,观察组在对照组基础上给予皮肤修护无菌敷料治疗。比较两组治疗效果、皮肤状态、红斑情况、治疗满意度、不良反应发生情况。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.001)。治疗前,两组皮肤厚度、皮肤回声密度比较,差异无统计学意义(P>0.05);治疗后,两组皮肤厚度小于治疗前,且观察组小于对照组,两组皮肤回声密度大于治疗前,且观察组大于对照组,差异有统计学意义(P<0.001)。治疗前,两组临床医师红斑评估量表(CEA)评分比较,差异无统计学意义(P>0.05);治疗后,两组CEA评分低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总满意度高于对照组,差异有统计学意义(P<0.001)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:多西环素联合皮肤修护无菌敷料治疗玫瑰痤疮的临床效果较好,可改善患者皮肤状态、红斑情况,提高患者满意度,且安全性较高。Objective:To investigate the clinical effect of doxycycline combined with skin repair sterile dressings in the treatment of acne rosacea.Methods:A total of 78 patients with acne rosacea admitted to the Department of Dermatology of the Third Affili-ated Hospital of Jinzhou Medical University from August 2019 to August 2021 were selected as the study subjects.They were ran-domly divided into two groups,with 39 cases in each group.The control group was treated with doxycycline,and the observation group was treated with skin repair sterile dressings on the basis of the control group.The treatment effect,skin condition,erythema,treatment satisfaction,and adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).Before treatment,there was no significant difference in skin thickness and skin echo density between the two groups(P>0.05).After treat-ment,the skin thickness in the two groups was smaller than that before treatment,and this index in the observation group was smaller than that in the control group,while the skin echo density in the two groups was greater than that before treatment,and this index in the observation group was greater than that in the control group,and the difference was statistically significant(P<0.001).Before treatment,there was no significant difference in the Clinician Erythema Assessment scale(CEA)score between the two groups(P>0.05).After treatment,the CEA score in the two groups was lower than that before treatment,and the score in the obser-vation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The total satisfaction with treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion

关 键 词：皮肤修复无菌敷料 玫瑰痤疮 多西环素 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]