肺炎球菌性疾病高风险儿童肺炎球菌疫苗免疫策略  

Immunization strategies for pneumococcal vaccines in children at high risk for pneumococcal disease

作　　者：包黎明 郑徽[1,2] 尹遵栋[1,2] BAO Liming;ZHENG Hui;YIN Zundong(National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease,Chinese Center for Disease Control and Prevention,Beijing 102206,China;不详)

机构地区：[1]中国疾病预防控制中心传染病溯源预警与智能决策全国重点实验室,北京102206 [2]中国疾病预防控制中心免疫规划中心

出　　处：《中国预防医学杂志》2024年第3期272-278,共7页Chinese Preventive Medicine

基　　金：真实世界疫苗干预(0557);公共卫生应急反应机制的运行(102393220020010000017)。

摘　　要：肺炎球菌性疾病是全球重大的公共卫生问题,患有某些基础疾病的儿童更容易发生该疾病,为肺炎球菌性疾病高风险儿童。接种肺炎球菌疫苗是预防控制肺炎球菌性疾病的有效手段。本研究通过对肺炎球菌疫苗不同免疫策略在肺炎球菌性疾病高风险儿童中免疫原性和有效性及其在真实世界的应用进行综述,为中国建立更为完善的免疫规划程序提供依据。Pneumococcal disease is a major global public health issue,and children with certain underlying conditions are more susceptible to this disease,making them high-risk for pneumococcal diseases.The pneumococcal vaccine is an effective measure to prevent and control pneumococcal diseases.This article reviews the immunogenicity and effectiveness of different immunization strategies for pneumococcal vaccines in children at high risk of pneumococcal disease and its real-world applications,aiming to provide a basis for establishing a better immunization program in China.

关 键 词：肺炎球菌性疾病 肺炎球菌疫苗 免疫策略 高风险儿童 

分 类 号：R186[医药卫生—流行病学]