单纯性卵巢囊肿采取当归芍药散合桂枝茯苓丸加减治疗的效果及对卵巢囊肿体积的影响  

Effect of modified Danggui Shaoyao Powder and Guizhi Fuling Pill on simple ovarian cyst and its influence on the volume of ovarian cyst

作　　者：张福梅 ZHANG Fu-mei(Shan County Hospital of Traditional Chinese Medicine,Heze 274300,China)

机构地区：[1]山东省菏泽市单县中医医院,274300

出　　处：《中国现代药物应用》2024年第9期148-151,共4页Chinese Journal of Modern Drug Application

摘　　要：目的研究当归芍药散合桂枝茯苓丸加减治疗单纯性卵巢囊肿的效果及对卵巢囊肿体积的影响。方法选取84例单纯性卵巢囊肿患者,以治疗方案不同分为对照组及观察组,每组42例。对照组单纯应用桂枝茯苓丸(汤剂)治疗,观察组应用当归芍药散合桂枝茯苓丸加减治疗。比较两组疗效及治疗前后的中医证候积分、卵巢囊肿体积、性激素[雌二醇(E_(2))、促黄体生成素(LH)、促卵泡生成素(FSH)]水平。结果观察组总有效率95.24%高于对照组的78.57%(P<0.05)。治疗后,两组小腹刺痛、带下量多、腹部胀痛、月经不调、神疲乏力、婚久不孕积分均低于本组治疗前,且观察组小腹刺痛、带下量多、腹部胀痛、月经不调、神疲乏力、婚久不孕积分分别为(1.27±0.32)、(1.35±0.37)、(1.08±0.27)、(0.65±0.18)、(0.61±0.15)、(0.51±0.12)分,低于对照组的(1.96±0.45)、(2.14±0.51)、(1.78±0.43)、(0.93±0.32)、(0.92±0.29)、(0.82±0.24)分(P<0.05)。治疗后1、2、3个月,两组卵巢囊肿体积均小于本组治疗前,且观察组卵巢囊肿体积分别为(4.21±0.61)、(3.07±0.37)、(2.04±0.19)cm^(3),小于对照组的(5.29±0.86)、(4.28±0.59)、(2.95±0.34)cm^(3)(P<0.05)。治疗后,两组E2、LH水平低于本组治疗前,FSH水平高于本组治疗前,且观察组E_(2)(264.98±11.75)pmol/L、LH(8.34±1.24)U/L低于对照组的(301.56±16.81)pmol/L、(11.03±2.43)U/L,FSH(6.01±1.26)U/L高于对照组的(4.75±0.83)U/L(P<0.05)。结论对单纯性卵巢囊肿患者而言,应用当归芍药散合桂枝茯苓丸加减治疗效果确切,可改善中医证候,缩小囊肿体积,调节性激素,值得应用。Objective To study the effect of modified Danggui Shaoyao Powder and Guizhi Fuling Pill on simple ovarian cyst and its influence on the volume of ovarian cyst.Methods 84 patients with simple ovarian cyst were selected and divided into a control group and an observation group according to different treatment plan,with 42 cases in each group.Patients in the control group were treated with Guizhi Fuling Pill(decoction)alone,and patients in the observation group were treated with modified Danggui Shaoyao Powder and Guizhi Fuling Pill.Both groups were compared in terms of efficacy,and traditional Chinese medicine syndrome score,volume of ovarian cyst,sex hormone[estradiol(E2),luteinizing hormone(LH),follicle-stimulating hormone(FSH)]levels before and after treatment.Results The total effective rate of the observation group was 95.24%,which was higher than the control group's 78.57%(P<0.05).After treatment,the scores of lower abdomen tingling,excessive vaginal discharge,abdominal distension,irregular menstruation,fatigue,and prolonged infertility in both groups were all lower than those before treatment in this group;in the observation group,the scores of scores of lower abdomen tingling,excessive vaginal discharge,abdominal distension,irregular menstruation,fatigue,and prolonged infertility were(1.27±0.32),(1.35±0.37),(1.08±0.27),(0.65±0.18),(0.61±0.15)and(0.51±0.12)points,which were lower than(1.96±0.45),(2.14±0.51),(1.78±0.43),(0.93±0.32),(0.92±0.29)and(0.82±0.24)points in the control group(P<0.05).At 1,2 and 3 months after treatment,the volume of ovarian cysts in both groups was smaller than that before treatment in this group;the volume of ovarian cyst in the observation group were(4.21±0.61),(3.07±0.37)and(2.04±0.19)cm^(3),which were smaller than(5.29±0.86),(4.28±0.59)and(2.95±0.34)cm^(3) in the control group(P<0.05).After treatment,E_(2) and LH levels in both groups were lower than those before treatment in this group,and FSH levels were higher than that before treatment in this group;the obser

关 键 词：单纯性卵巢囊肿 当归芍药散合桂枝茯苓丸加减 卵巢囊肿体积 

分 类 号：R273[医药卫生—中西医结合]