微信平台健康管理模式联合小剂量阿托伐他汀对代谢综合征肥胖患者血脂血糖、生活质量、负面情绪的影响  

The combined impact of the WeChat platform health management model and low-dose atorvastatin on lipid and glucose profiles,quality of life,and negative emotions in patients with metabolic syndrome and obesity

作　　者：徐李香 屠伟平 陶峰 XU Lixiang;TU Weiping;TAO Feng(Department of Nursing,Shangyu People's Hospital in Shaoxing,Shaoxing 312300,Zhejiang Province,China;Department of Endocrine Metabolism,Shangyu People's Hospital in Shaoxing,Shaoxing 312300,Zhejiang Province,China;Department of Respiratory Medicine,the First Hospital of Jiaxing,Jiaxing 314000,Zhejiang Province,China)

机构地区：[1]绍兴市上虞人民医院护理部,浙江绍兴312300 [2]绍兴市上虞人民医院内分泌代谢科,浙江绍兴312300 [3]嘉兴市第一医院呼吸内科,浙江嘉兴314000

出　　处：《中国药师》2024年第4期603-611,共9页China Pharmacist

基　　金：嘉兴市公益性研究计划项目(2021AD30177)。

摘　　要：目的 评价微信平台健康管理模式联合小剂量阿托伐他汀对代谢综合征肥胖患者血脂血糖、生活质量、负面情绪的影响。方法 回顾性分析2022年6月至2023年6月在绍兴市上虞人民医院就诊的代谢综合征肥胖患者资料,根据患者院外健康管理方式分为对照组和试验组,对照组接受阿托伐他汀联合常规健康管理治疗,试验组接受阿托伐他汀联合基于微信平台健康管理模式治疗。分别比较两组患者干预前和干预后3个月、6个月的血糖、血脂相关指标;干预前和干预后6个月的负面情绪、生活质量及自我管理能力。结果 研究共纳入160例患者,对照组85例,试验组75例。干预后,两组患者3个月、6个月的空腹血糖(FBG)、餐后2小时血糖(2hPBG)、糖化血红蛋白(HbA1c)、低密度脂蛋白(LDL-C)、甘油三酯(TG)与总胆固醇(TC)均较干预前显著降低,且试验组低于对照组(P <0.05);而高密度脂蛋白(HDL-C)较干预前显著升高,且试验组高于对照组(P <0.05)。与干预前相比,两组患者6个月后的焦虑自评量表(SAS)、抑郁自评量表(SDS)低于干预前,各项生活质量评分高于干预前,且试验组自我管理能力显著高于对照组(P <0.05)。结论 微信平台健康管理模式联合小剂量阿托伐他汀治疗可有效改善代谢综合征肥胖患者的血脂、血糖、负面情绪、自我管理能力和生活质量,值得在临床推广。Objective To evaluate the impact of the WeChat platform health management model combined with low-dose atorvastatin on lipid and glucose profiles,quality of life,and negative emotions in patients with metabolic syndrome and obesity.Methods The data of obese patients with metabolic syndrome who were treated at Shangyu People's Hospital of Shaoxing from June 2022 to June 2023 were retrospectively analyzed.The patients were divided into a control group and an experimental group according to their out-of-hospital health management methods.The control group received atorvastatin combined with conventional health management treatment,and the experimental group received atorvastatin combined with a health management model based on the WeChat platform.The blood glucose and lipid-related indicators were compared between the two groups before and 3 months and 6 months after intervention.Negative emotions and quality of life were compared before and 6 months after intervention,and self-management ability was compared 6 months after intervention.Results A total of 160 patients were included in the study,with 85 patients in the control group and 75 patients in the experimental group.After the intervention,the fasting blood glucose(FBG),2-hour postprandial blood glucose(2hPBG),glycated hemoglobin(HbA1c),low-density lipoprotein(LDL-C),triglyceride(TG)and total cholesterol(TC)of the two groups of patients at 3 months and 6 months)were significantly lower than before intervention,and the above indicators of the experimental group were lower than those of the control group(P<0.05);while high-density lipoprotein(HDL-C)was significantly higher than that before intervention,and HDL-C in the observation group was higher than that of the control group(P<0.05).Compared with pre-treatment,the anxiety self-rating scale(SAS)and depression self-rating scale(SDS)scores were siginficantly lower,and various quality of life scores for both groups significantly higher 6 months after intervention(P<0.05),and the self-management ability of the exp

关 键 词：微信平台健康管理模式 阿托伐他汀 代谢综合征肥胖 血糖血脂 生活质量 

分 类 号：R589.2[医药卫生—内分泌]