鼻后神经切断术治疗对复发性鼻窦炎伴息肉患者的影响  

Effect of posterior nasal Nerve Resection on Patients with recurrent Sinusitis and Polyps

作　　者：孙梅英 SUN Meiying(Department of Nose and Throat,Zhengzhou Minsheng Ear,Nose and Throat Hospital,Zhengzhou Henan 450000,China)

机构地区：[1]郑州民生耳鼻喉医院鼻咽喉科,河南郑州450000

出　　处：《临床研究》2024年第6期65-68,共4页Clinical Research

摘　　要：目的分析鼻后神经切断术治疗对复发性鼻窦炎伴息肉患者的影响。方法将2020年6月至2023年12月收治的76例复发性鼻窦炎伴息肉患者纳入为研究对象,依据随机单双数抽签法分组,38例单数者入对照组,实施功能性鼻内镜手术治疗;38例双数者入研究组,实施功能性鼻内镜手术+鼻后神经切断术治疗。对比两组一年内疾病复发率、治疗前后鼻腔鼻窦结局测试-20(SNOT-20)评分、Lund-Kennedy鼻内镜评分及血清炎性因子C反应蛋白(CRP)水平。结果研究组术后1年内疾病复发率(2.63%)低于对照组(31.58%),差异具有统计学意义(P<0.05);治疗前两组SNOT-20评分对比,差异无统计学意义(P>0.05),治疗后两组SNOT-20评分低于治疗前,且研究组SNOT-20评分低于对照组,差异具有统计学意义(P<0.05);治疗前两组Lund-Kennedy鼻内镜评分对比差异无统计学意义(P>0.05),治疗后两组Lund-Kennedy鼻内镜评分低于治疗前,且研究组Lund-Kennedy鼻内镜评分低于对照组,差异具有统计学意义(P<0.05);治疗前两组CRP水平对比差异无统计学意义(P>0.05),治疗后两组CRP水平低于治疗前,且研究组低于对照组,差异具有统计学意义(P<0.05)。结论复发性鼻窦炎伴息肉患者采取鼻后神经切断术治疗可降低疾病复发率、减少疾病相关症状、降低炎性因子,值得应用。Objective To analyze the impact of posterior nasal nerve resection on patients with recurrent sinusitis and polyps.Methods A total of 76 patients with recurrent sinusitis and polyps treated from June 2020 to December 2023 were included as the study subjects.They were randomly divided into two groups using a single or even number drawing method,with 38 odd numbered patients assigned to the control group for functional endoscopic surgery;Another 38 even numbered individuals were enrolled in the study group and underwent functional endoscopic surgery combined with posterior nasal nerve resection for treatment.The disease recurrence rate,sino-nasal outcome test-20(SNOT-20)score,Lund-Kennedy nasal endoscopy score,and serum inflammatory factor C-reactive protein(CRP)levels were compared between two groups within one year before and after treatment.Results The disease recurrence rate within 1 year after surgery in the study group(2.63%)was lower than that in the control group(31.58%),and the difference was statistically significant(P<0.05);Before treatment,there was no statistically significant difference in SNOT-20 scores between the two groups(P>0.05).After treatment,the SNOT-20 scores of the two groups were lower than those before treatment,and the SNOT-20 scores of the study group were lower than those of the control group,with a statistically significant difference(P<0.05);There was no statistically significant difference in the Lund-Kennedy nasal endoscopy scores between the two groups before treatment(P>0.05).After treatment,the Lund Kennedy nasal endoscopy scores of the two groups were lower than those before treatment,and the Lund-Kennedy nasal endoscopy scores of the study group were lower than those of the control group,with a statistically significant difference(P<0.05);There was no statistically significant difference in CRP levels between the two groups before treatment(P>0.05).After treatment,the CRP levels in the two groups were lower than those before treatment,and the study group was lower than the con

关 键 词：鼻后神经切断术 复发性鼻窦炎 息肉 炎性因子 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]