白苓止痛方治疗慢性紧张性头痛的随机对照研究  

Randomized Controlled Study of Bailing Zhitong Prescription in Treatment of Chronic Tension Headache

作　　者：冯欣悦 回春[2] 李秀玲[2] 刘亚芬[2] 孙莉[2] FENG Xinyue;HUI Chun;LI Xiuling;LIU Yafen;SUN Li(Chinese Medicine School,Changchun University of Chinese Medicine,Changchun 130117,China;Jilin Academy of Chinese Medicine Sciences,Changchun 130021,China)

机构地区：[1]长春中医药大学中医学院,吉林长春130117 [2]吉林省中医药科学院,吉林长春130021

出　　处：《基层中医药》2024年第4期48-54,共7页Basic Traditional Chinese Medicine

基　　金：吉林省科技发展计划项目(20210204039YY)。

摘　　要：目的基于祛湿化痰、缓急止痛法观察白苓止痛方对慢性紧张性头痛(CTTH)(痰湿内蕴型)患者的影响。方法根据临床资料,选择2022年1—12月就诊于吉林省中医药科学院的72名符合标准患者,采用随机数字表法分为两组,各36例。治疗组给予盐酸乙哌立松片+白苓止痛方,对照组给予盐酸乙哌立松片,治疗4周后,分别对两组患者的疼痛程度、每月发作次数、每次头痛持续时间、总的疼痛评分,以及汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分进行比较。结果69例患者完成了本项研究,治疗组35例,对照组34例。治疗后,治疗组总有效率(94.29%)高于对照组(52.94%,P<0.01);疼痛程度、每月发作次数、每次头痛持续时间、总的疼痛评分,以及HAMA和HAMD评分均低于对照组(P<0.01);两组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论应用白苓止痛方能明显改善CTTH(痰湿内蕴型)患者的疼痛程度,降低其发作频率,缩短其持续时间,且安全性较佳。Objective Using the method of dispelling dampness and resolving phlegm,easing urgency and relieving pain,this paper aimed to observe the effect of Bailing Zhitong prescription on patients with chronic tension-type headache(CTTH)of the internal retention of phlegm and dampness pattern.Methods Based on the clinical data,72 patients who met the criteria and visited Jilin Academy of Chinese Medicine Sciences from January 2022 to December 2022 were selected and randomly divided into two groups,with 36 cases in each group.Patients in the treatment group were given Eperisone Hydrochloride Tablets plus Bailing Zhitong prescription,and those in the control group were given Eperisone Hydrochloride Tablets.After four weeks of treatment,the pain level,the number of monthly attacks,the duration of each headache,and the scores of the Hamilton Anxiety Scale(HAMA)and the Hamilton Depression Scale(HAMD)of the patients in the two groups were compared,respectively.Results 69 patients completed this study,with 35 from the treatment group and 34 from the control group.After treatment,the total effective rate of the treatment group(94.29%)was higher than that of the control group(52.94%,P<0.01),with the pain level,the number of monthly attacks,the duration of each headache,and the HAMA and HAMD scores lower than those of the control group(P<0.01).There was no statistically significant difference in the incidence rate of adverse reactions between the two groups(P>0.05).Conclusion The application of Bailing Zhitong prescription can significantly moderate the pain level of patients with CTTH(internal retention of phlegm and dampness pattern),reduce the frequency of disease attacks,shorten headache duration,and have fewer side effects.

关 键 词：白苓止痛方 痰湿内蕴 慢性紧张性头痛 随机对照研究 

分 类 号：R47[医药卫生—护理学]