MRI正中矢状面对儿童胼胝体径线的测量研究  

Measurement of the diameter of the corpus callosum in children on the midsagittal plane of MRI

作　　者：陆宽 邓杰 郑勇 邱丽华 LU Kuan;DENG Jie;ZHENG Yong;QIU Lihua(Department of Radiology,the Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan Province 646000,China;Medical Imaging Center,the Second People’s Hospital of Yibin,Yibin,Sichuan Province 644000,China;Department of Radiology,the Fourth People’s Hospital of Yibin,Yibin,Sichuan Province 644000,China;Department of Radiology,Sichuan Provincial Maternity and Child Health Care Hospital,Chengdu 615000,China;Neurographic Big Data Research Center,the Second People’s Hospital of Yibin,Yibin,Sichuan Province 644000,China)

机构地区：[1]西南医科大学附属医院放射科,四川泸州646000 [2]宜宾市第二人民医院医学影像中心,四川宜宾644000 [3]宜宾市第四人民医院放射科,四川宜宾644000 [4]四川省妇幼保健院放射科,四川成都615000 [5]宜宾市第二人民医院·神经影像大数据研究中心,四川宜宾644000

出　　处：《实用放射学杂志》2024年第4期629-632,658,共5页Journal of Practical Radiology

摘　　要：目的采用高分辨率MRI正中矢状面图像测量0~14岁儿童胼胝体各径线值,找到不同年龄儿童胼胝体各径线的正常参考值。方法回顾性选取967例颅脑MRI检查结果正常的儿童影像学数据,按年龄段分组,于颅脑正中矢状面测量胼胝体的前后径(APD)、膝部厚度(GT)、体部厚度(BT)、峡部厚度(IT)、压部厚度(ST)以及枕额径(FOD)。测量不同年龄儿童颅脑正中矢状面胼胝体各径线值,对其进行与年龄的相关性分析。结果APD、GT、BT、IT、ST及FOD与年龄均呈正相关(r=0.660、0.590、0.528、0.521、0.660、0.597,P<0.01)。在胼胝体各亚区中IT变异度最大,GT、ST的增长高峰期出现在2岁前。结论建立儿童胼胝体不同亚区正常参考值范围,可帮助精准评估胼胝体发育情况,有利于对胼胝体相关疾病预后进行评价。Objective To measure the diameter of the corpus callosum in children aged 0-14 years using midsagittal high-resolution MRI,and to find the normal reference values of the diameter of the corpus callosum in children of different ages.Methods The imaging data of 967 children with normal brain MRI were retrospectively selected and grouped according to age.The anteroposterior diameter(APD),thickness of the genu(GT),thickness of the body(BT),thickness of the isthmus(IT),thickness of the splenium(ST)and fronto-occipital diameter(FOD)of the corpus callosum were measured on the midsagittal plane of the brain.The diameters of the corpus callosum on the midsagittal plane of the brain of children at different ages were measured.The correlation analysis between the diameter of the corpus callosum and age were performed.Results The APD,GT,BT,IT,ST and FOD were positively correlated with age(r=0.660,0.590,0.528,0.521,0.660,0.597,P<0.01).The IT variation was the greatest in the subregions of the corpus callosum.The growth peak of GT and ST of corpus callosum appeared before 2 years of age.Conclusion The establishment of the normal reference value of different subregions of the corpus callosum in children can help to accurately evaluate the development of the corpus callosum,which is conducive to the evaluation of the prognosis of diseases related to the corpus callosum.

关 键 词：磁共振成像 儿童 胼胝体 

分 类 号：R445.2[医药卫生—影像医学与核医学] R816.92[医药卫生—诊断学] R322.81[医药卫生—临床医学]