3.0T甲状腺TSE T2WI Fast Dixon、Dixon和BLADE序列的比较研究  

A comparative study of thyroid TSE T2WI at 3.0T:Fast Dixon,Dixon,and BLADE sequences

作　　者：赵建秀 石清磊 王晓烨 郁斌博 段影 ZHAO Jianxiu;SHI Qinglei;WANG Xiaoye;YU Binbo;DUAN Ying(Department of Radiology,Beijing Universal Medical Imaging Diagnostic Center,Beijing 100071,China;Siemens Healthcare,Beijing 100102,China)

机构地区：[1]北京全景德康医学影像诊断中心影像科,北京100071 [2]西门子医疗系统有限公司北京分公司,北京100102

出　　处：《实用放射学杂志》2024年第4期654-658,共5页Journal of Practical Radiology

摘　　要：目的通过比较研究基于快速自旋回波(TSE)的Fast Dixon、Dixon和BLADE序列的甲状腺MR T2WI图像质量,探讨Fast Dixon序列在提高甲状腺TSE T2WI图像质量中的价值。方法前瞻性选取11例健康志愿者行颈部MR检查,采用客观指标和主观评分相结合的方法进行图像质量的评估,客观指标包括双侧甲状腺、肌肉的信噪比(SNR)、对比噪声比(CNR);主观指标包括整体图像质量、脂肪抑制的均匀性、甲状腺边缘清晰度、甲状腺周围肌肉边缘清晰度、颈部图像噪声、图像背景噪声、鼻咽部图像质量7个方面,由2位具有10年以上甲状腺诊断经验的诊断医师依据5分法独立进行评估,并进行观察者一致性分析,采用Spearman相关系数进行观察者一致性分析;采用SPSS 22.0软件进行统计学分析,计量资料进行正态分布和方差齐性检验,主观指标采用Kruskal-Wallis one-way ANOVA进行统计分析并进行事后两两比较分析,P<0.05为差异有统计学意义。结果11例健康志愿者双侧甲状腺及肌肉的SNR,Fast Dixon序列显著高于Dixon和BLADE序列;双侧的CNR,Fast Dixon序列亦显著高于Dixon和BLADE序列。在7个主观评分指标方面,Fast Dixon序列同样具有显著的优势(P<0.001)。结论Fast Dixon序列在甲状腺解剖成像中可以提供更清晰的图像质量,对甲状腺病变的显示和评估具有重要应用价值。Objective To explore the value of Fast Dixon in improving the quality of thyroid turbo spin echo(TSE)T2WI images via comparing the quality of thyroid MR T2WI images based on Fast Dixon,Dixon,and BLADE sequences.Methods The prospective study included 11 healthy volunteers,who underwent neck MR scanning.The evaluation of image quality was performed via a combination of objective measures and subjective ratings.Objective measures included signal-to-noise ratio(SNR)of bilateral thyroid and muscles,and contrast-to-noise ratio(CNR).Subjective measures included overall image quality,uniformity of fat suppression,sharpness of thyroid margins and muscles surrounding the thyroid,image noise in the neck region,image background noise,and image quality of the nasopharynx.Two diagnostic physicians with over 10 years of thyroid diagnostic experience independently evaluated the images via a 5-point scale.Inter-observer agreement was analyzed via Spearman correlation coefficient.Statistical analysis was performed using SPSS 22.0 software,including normality and homogeneity of variance tests for continuous data.Kruskal-Wallis one-way ANOVA was used for statistical analysis of subjective measures,followed by post hoc pairwise comparisons.A significance level of P<0.05 was considered statistically significant.Results Eleven healthy volunteers,the SNR of bilateral thyroid and muscles was significantly higher in Fast Dixon sequence than that in Dixon and BLADE sequences.For bilateral CNR,Fast Dixon sequence was also significantly higher than that of Dixon and BLADE sequences.Fast Dixon sequence also had significant advantages in seven subjective ratings indicators(P<0.001).Conclusion The Fast Dixon sequence shows the highest image quality and important application value in the display and evaluation of thyroid lesions.

关 键 词：甲状腺 磁共振成像 Fast Dixon DIXON BLADE 

分 类 号：R322.51[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]