器官保存与修复技术的研究进展  

Research advances in organ preservation and restoration techniques

作　　者：赵闻雨 朱有华 Zhao Wenyu;Zhu Youhua(Department of Organ Transplantation,The First Affiliated Hospital of Naval Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学第一附属医院器官移植科,上海200433

出　　处：《中华器官移植杂志》2024年第2期68-74,共7页Chinese Journal of Organ Transplantation

基　　金：海军军医大学第一附属医院临床科技创新探索项目。

摘　　要：为了应对日益严峻的供者器官短缺问题,大量边缘供者器官被应用于临床,这对传统的器官保存技术提出了更高的要求。静态低温保存作为目前器官保存的标准方法,已无法满足边缘供者器官保存的需要。而机械灌注保存不但可以提高器官保存的效果、延长器官保存的时限,还可为器官质量评估和损伤修复提供平台,目前已成为器官保存领域的主要发展方向。本文就器官保存与修复技术的研究进展作一综述。A popular use of marginal donor organs requires an optimization of organ preservation strategies.The current standards of organ preservation and static cold storage are insufficient to fulfill the demands of marginal donor organ preservation.Machine perfusion has been a primary development direction in organ preservation.Capable of improving preservation effectiveness and prolonging preservation time,it has the potential of becoming a practical platform for ex-vivo organ assessment and injury restoring.This review summarized the latest advances in organ preservation and restoration techniques.

关 键 词：器官保存 机械灌注 扩大标准供者 心脏死亡供者 

分 类 号：R617[医药卫生—外科学]