中国肾脏移植免疫监测临床诊疗指南(2023版)  

Chinese Guideline for the diagnosis and management of immune monitoring after kidney transplantation(2023 edition)

作　　者：中华医学会器官移植学分会 中国医药生物技术协会移植技术分会 陈刚[2] 朱兰 郭志良 张雷 Branch of Organ Transplantation,Chinese Medical Association;Society of Transplant Technology,China Medical Biotechnology Association;Chen Gang(不详;Organ Transplantation Center,Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030)

机构地区：[1]不详 [2]华中科技大学同济医学院附属同济医院器官移植研究所,武汉430030 [3]海军军医大学第一附属医院

出　　处：《中华器官移植杂志》2024年第3期136-148,共13页Chinese Journal of Organ Transplantation

基　　金：中国医学科学院中央级公益性科研院所基本科研业务费专项(2023-PT320-07)。

摘　　要：预防肾脏移植排斥反应离不开免疫抑制剂,但免疫抑制过度相关的感染也会影响移植肾和移植受者的存活。主动监测肾脏移植受者的免疫状态,有利于早期发现排斥反应风险或感染风险,有助于指导临床调整免疫抑制强度。本指南围绕我国目前可行的免疫监测指标进行推荐和说明,以期有利于提高移植肾和移植受者的长期存活。Immunosuppressive agents are essential for the prevention of renal allograft rejection,but infections associated with over immunosuppression can also affect the patient and graft survival.Regular monitoring of the recipient's immune status is conducive to early identifying the risky of rejection or infection,and can be helpful to guide clinical adjustment of immunosuppressive therapy.This guideline recommends and explains the currently available immune surveillance methods in order to ultimately improve the long-term survival of the kidney allografts and recipients.

关 键 词：肾移植 免疫监测 排斥反应 感染 供者特异性抗体 指南 

分 类 号：R699.2[医药卫生—泌尿科学]