中性粒细胞外诱捕网在抗磷脂综合征中作用的研究进展  

Research progress of the role of neutrophil extracellular traps in antiphospholipid syndrome

作　　者：张烨潇 徐霖婕 乌兰 ZHANG Yexiao;XU Linjie;WU Lan(Department of Gynecology and Obstetrics,Women’s Hospital of Nanjing Medical University,Nanjing Women and Children’s Healthcare Hospital,Nanjing,Jiangsu 210004,China)

机构地区：[1]南京医科大学附属妇产医院/南京市妇幼保健院妇产科,江苏南京210004

出　　处：《中国优生与遗传杂志》2024年第3期649-653,共5页Chinese Journal of Birth Health & Heredity

摘　　要：抗磷脂综合征(APS)是一种系统性自身免疫性疾病,以血栓形成或产科并发症为主要特征。最近越来越多的证据表明,中性粒细胞,尤其是中性粒细胞外诱捕网(NETs)在APS的致病过程中发挥着重要作用。本文对NETs在APS中的作用进行了综述,旨在帮助人们更好地了解APS的发病机制,从而制定更有效、更个性化的治疗方案。Antiphospholipid syndrome(APS),a systemic autoimmune disease,is principally characterized by thrombosis and obstetric complications.Recently,increasing evidence shows that neutrophils,especially neutrophil extracellular traps(NETs)play a crucial role in pathological process of APS.In order to help understand the pathogenesis of APS,this article makes a literature review for the role of NETs in APS,thus helps to institute more effective and personalized heal project.

关 键 词：抗磷脂综合征 中性粒细胞外诱捕网 中性粒细胞 抗磷脂抗体 产科并发症 

分 类 号：R593.2[医药卫生—内科学]