A Self-Healing Optoacoustic Patch with High Damage Threshold and Conversion Efficiency for Biomedical Applications  

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作  者:Tao Zhang Cheng-Hui Li Wenbo Li Zhen Wang Zhongya Gu Jiapu Li Junru Yuan Jun Ou-Yang Xiaofei Yang Benpeng Zhu 

机构地区:[1]School of Integrated Circuit,Wuhan National Laboratory for Optoelectronics,Huazhong University of Science and Technology,Wuhan 430074,People’s Republic of China [2]State Key Laboratory of Coordination Chemistry,Collaborative Innovation Center of Advanced Microstructures,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,People’s Republic of China [3]National Institute of Dental and Craniofacial Research(NIDCR),National Institutes of Health(NIH),35A Convent Drive,Bethesda,MD 20892,USA [4]Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,People’s Republic of China

出  处:《Nano-Micro Letters》2024年第7期31-45,共15页纳微快报(英文版)

基  金:This work was supported by the Natural Science Foundation of China(Grant no.U22A20259,12102140);the Shenzhen Basic Science Research(No.JCYJ20200109110006136);the China Postdoctoral Science Foundation(No.2022M721258).We also thank the Analytical and Testing Center of Huazhong University of Science&Technology.

摘  要:Compared with traditional piezoelectric ultrasonic devices,optoacoustic devices have unique advantages such as a simple preparation process,anti-electromagnetic interference,and wireless long-distance power supply.However,current optoacoustic devices remain limited due to a low damage threshold and energy conversion efficiency,which seriously hinder their widespread applications.In this study,using a self-healing polydimethylsiloxane(PDMS,Fe-Hpdca-PDMS)and carbon nanotube composite,a flexible optoacoustic patch is developed,which possesses the self-healing capability at room temperature,and can even recover from damage induced by cutting or laser irradiation.Moreover,this patch can generate high-intensity ultrasound(>25 MPa)without the focusing structure.The laser damage threshold is greater than 183.44 mJ cm^(-2),and the optoacoustic energy conversion efficiency reaches a major achievement at 10.66×10^(-3),compared with other carbon-based nanomaterials and PDMS composites.This patch is also been successfully examined in the application of acoustic flow,thrombolysis,and wireless energy harvesting.All findings in this study provides new insight into designing and fabricating of novel ultrasound devices for biomedical applications.

关 键 词:Optoacoustic Self-healing PDMS Acoustic flow THROMBOLYTIC Wireless energy harvesting 

分 类 号:TB57[理学—物理]

 

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