Active Micro-Nano-Collaborative Bioelectronic Device for Advanced Electrophysiological Recording  

作　　者：Yuting Xiang Keda Shi Ying Li Jiajin Xue Zhicheng Tong Huiming Li Zhongjun Li Chong Teng Jiaru Fang Ning Hu 

机构地区：[1]Department of Chemistry,Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials,ZJU-Hangzhou Global Scientific and Technological Innovation Center,Zhejiang University,Hangzhou 310058,People’s Republic of China [2]School of Basic Medical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,People’s Republic of China [3]General Surgery Department,Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Children’s Health,Hangzhou 310052,People’s Republic of China [4]Department of Lung Transplantation and General Thoracic Surgery,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,People’s Republic of China [5]Department of Orthopedics,The Fourth Affiliated Hospital,Zhejiang University School of Medicine,Yiwu 322005,People’s Republic of China [6]School of Electronics and Information Technology,Sun Yat-Sen University,Guangzhou 510006,People’s Republic of China [7]Department of Obstetrics and Gynecology,The Tenth Affiliated Hospital,Southern Medical University,Dongguan 523059,People’s Republic of China [8]Dongguan Key Laboratory of Major Diseases in Obstetrics and Gynecology,Dongguan 523059,People’s Republic of China

出　　处：《Nano-Micro Letters》2024年第7期244-264,共21页纳微快报（英文版）

基　　金：The work is supported in part by the National Natural Science Foundation of China(Grant Nos.62171483,82061148011);Zhejiang Provincial Natural Science Foundation of China(Grant No.LZ23F010004);Hangzhou Agricultural and Social Development Research Key Project(Grant No.20231203A08);Doctoral Initiation Program of the Tenth Affiliated Hospital,Southern Medical University(Grant No.K202308).

摘　　要：The development of precise and sensitive electrophysiological recording platforms holds the utmost importance for research in the fields of cardiology and neuroscience.In recent years,active micro/nano-bioelectronic devices have undergone significant advancements,thereby facilitating the study of electrophysiology.The distinctive configuration and exceptional functionality of these active micro-nano-collaborative bioelectronic devices offer the potential for the recording of high-fidelity action potential signals on a large scale.In this paper,we review three-dimensional active nano-transistors and planar active micro-transistors in terms of their applications in electroexcitable cells,focusing on the evaluation of the effects of active micro/nano-bioelectronic devices on electrophysiological signals.Looking forward to the possibilities,challenges,and wide prospects of active micro-nano-devices,we expect to advance their progress to satisfy the demands of theoretical investigations and medical implementations within the domains of cardiology and neuroscience research.

关 键 词：Active micro/nano collaborative bioelectronic device Three-dimensional active nano-transistor Planar active microtransistor ELECTROPHYSIOLOGY 

分 类 号：TN03[电子电信—物理电子学] R318[医药卫生—生物医学工程]