Accelerated reconstruction of ZIF-67 with significantly enhanced glucose detection sensitivity  

作　　者：Huihui Jin Weihao Zeng Wei Qian Lun Li Pengxia Ji Zhengying Li Daping He 

机构地区：[1]School of Information Engineering,Wuhan University of Technology,Wuhan 430070,China [2]Hubei Engineering Research Center of RF-Microwave Technology and Application,Wuhan University of Technology,Wuhan 430070,China [3]State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology,Wuhan 430070,China

出　　处：《Nano Research》2024年第6期4737-4743,共7页纳米研究（英文版）

基　　金：the National Natural Science Foundation of China(Nos.22102128 and 22279097);the Fundamental Research Funds for the Central Universities(No.WUT:2022IVA168).

摘　　要：Research on metal-organic framework(MOF)-based non-enzymatic glucose sensors usually ignores the impact of the surface reconstruction degree of MOF on the activity of catalyzing glucose oxidation.In this work,we choose zeolitic imidazolate framework-67(ZIF-67),which is commonly used in glucose sensing,as a representative to investigate the influence of reconstruction degree on its structure and glucose catalytic performance.By employing the electrochemical activation strategy,the activity of ZIF-67 in catalyzing glucose gradually increased with the prolongation of the activation time,reaching the optimum after 2 h activation.The detection sensitivity of the activated ZIF-67 was 19 times higher than that of the initial ZIF-67,and the limit of detection(LOD)was lowered from 7 to 0.4μM.Our findings demonstrate that the oxidation degree of ZIF-67 deepened rapidly with continuously activation and was basically reconstructed to CoOOH after 2 h activation,accompanied by a morphological change from cuboctahedral to flower-like.Simultaneously,theoretical investigation revealed that ZIF-67 is not suitable as a stable glucose sensor electrode since the adsorbed glucose molecules hasten the dissociation of ligands and the breaking of Co-N bond in ZIF-67.Therefore,our work has important implications for the rational design of next-generation MOF-based glucose sensors.

关 键 词：zeolitic imidazolate framework-67(ZIF-67) glucose oxidation electrochemical activation RECONSTRUCTION COOOH 

分 类 号：O64[理学—物理化学]