闪光放射治疗中剂量测量研究现状的可视化分析  

Visualization analysis of study status of measuring the dose of radiotherapy for Flash-RT

作　　者：王宁 张世旭[2,3] 郭逸潇[4] 冉俊涛[1] Wang Ning;Zhang Shixu;Guo Yixiao;Ran Juntao(Department of Radiotherapy,The First Hospital of Lanzhou University,Lanzhou 730000,China;Frontier Science Center for Rare Isotopes,School of Nuclear Science and Technology,Lanzhou University,Lanzhou 730000,China;Department of Radiotherapy,Gansu Provincial Hospital,Lanzhou 730000,China)

机构地区：[1]兰州大学第一医院放疗科,兰州730000 [2]兰州大学教育部稀有同位素前沿科学中心,兰州730000 [3]兰州大学核科学技术学院,兰州730000 [4]甘肃省人民医院放疗科,兰州730000

出　　处：《中国医学装备》2024年第5期1-10,共10页China Medical Equipment

基　　金：国家自然科学基金地区项目基金(82360583);甘肃省科技计划重大专项(22ZD6FA050);兰州大学第一医院院内基金(XK-030202-389)。

摘　　要：目的:基于美国科学期刊网络索引(WOS)数据库,通过文献计量学方法对闪光放射治疗(Flash-RT)中剂量测量领域的研究现状、重点和趋势进行可视化分析和归纳总结,分析Flash-RT剂量测量的技术瓶颈。方法:在WOS数据库中,以“FLASH radiotherapy"or"ultra high dose rate”or“FLASH irradiation”,“dosimetric system”or“dosimeters”or“dosimetry”为主题词,检索WOS数据库核心合集收录的所有Flash-RT剂量测量的研究相关文献。运用WOS数据库自带引文分析功能和Citespace可视化软件(Version6.2)对纳入的86篇Flash-RT剂量测量文献发文趋势、来源和研究重点进行可视化分析,并绘制相应可视化知识图。结果:经筛选的86篇文献主要发表于2015年1月至2023年11月,其中论文78篇、综述8篇。发文量前3位的国家分别为美国(38篇)、法国(19篇)及意大利(19篇)。研究重点聚类为切伦科夫(Cherenkov),放射治疗(radiotherapy),被动式剂量计(passive dosimeter),传统放射治疗(conventional radiation)、激光粒子加速度(laser particle acceleration)、电离室(ionization chamber)和质子治疗(protontherapy)。Flash-RT剂量测量的研究目前集中于Flash-RT辐射源、剂量率和剂量测量设备与方法相关方向。结论:Flash-RT是放射治疗基础领域具有关键性突破的新技术,该技术的临床转化过程中面临着很多的困难和挑战。随着科技的不断进步和临床大数据的积累,精准高效的剂量测量方法和程序将促进实现Flash-RT试验研究和装置技术的更新迭代,并能够成功实现该技术的临床应用。Objective: To conduct visualization analysis, induction and summary for the study status, focus and trend in the dose measurement field of flash radiotherapy(Flash-RT) through bibliometric methods on the basis of the Web of Science Collection(WOS), and analyze the technical bottleneck of Flash-RT dose measurement. Methods: In the WOS database, the( "FLASH radiotherapy" or "ultra high dose rate" or "FLASH irradiation") and TS=( "dosimetric system" or "dosimeters" or "dosimetry") were used as the theme terms, and all relevant literatures about the study of Flash-RT dose measurement that were included in the Core Collection of WOS database were retrieved. The citation analysis function of WOS and Citespace software(Version 6.2) were used to conduct visualization analysis for the publication trends, sources and research focus of the included literature of Flash-RT dose measurement, and to draw corresponding visualization knowledge maps. Results: The literatures were mainly published during January 2015 and November 2023, and a total of 86 papers were included in the analysis by screening, which included 78 articles and 8 reviews. The top three countries in terms of publication volume were respectively the United States(38 papers), France(19 papers)and Italy(19 papers). The research focuses were respectively Cherenkov, radiotherapy, passive dosimeter, conventional radiation, laser particle acceleration, ionization chamber and proton therapy as cluster analysis. Currently, the study of Flash-RT dose measurement mainly focused on the relevant fields included Flash-RT radiation source, dose rate, and the equipment and method of dose measurement. Conclusion: Flash-RT is a new technology with a key breakthrough in the basic field of radiotherapy, and this technique faces many difficulties and challenges in the clinical translation process of this technique. With the continuous development of science and technique, and deepeningaccumulation of related researchclinical big data, the method and procedure of accurate and effic

关 键 词：闪光放射治疗(Flash-RT) 剂量测量 CiteSpace软件 可视化分析 科学期刊网络索引(WOS) 

分 类 号：R815[医药卫生—放射医学]