输尿管镜钬激光碎石术联合N-trap拦截网篮对治疗中上段输尿管结石的效果评价  

Evaluation on curative effect of ureteroscopic holmium laser lithotripsy combined with N-trap intercepted basket in treating middle and upper ureteral stones

作　　者：徐瑞 王宇 唐召 郭松林 Xu Rui;Wang Yu;Tang Zhao;Guo Songlin(Department of Urology,The Second Affiliated Hospital of Wannan Medical College,Wuhu 241000,China)

机构地区：[1]皖南医学院第二附属医院泌尿外科,芜湖241000

出　　处：《中国医学装备》2024年第5期26-30,41,共6页China Medical Equipment

基　　金：安徽省卫生健康委科研项目重点项目(AHWJ2021a003)。

摘　　要：目的:研究输尿管镜钬激光碎石术联合结石捕获取出器N-trap拦截网篮在治疗中上段输尿管结石的临床效果。方法:前瞻性选择2020年9月至2022年9月在皖南医学院第二附属医院泌尿外科诊治的112例输尿管中上段结石患者,按照随机数表法分为对照组和观察组,每组56例。对照组单独给予输尿管镜钬激光碎石术治疗,观察组给予输尿管镜钬激光碎石术联合N-trap拦截网篮治疗,比较两组手术相关指标和结石清除效果,肾功能指标、术后肾积、术后复发与术后并发症情况。采用威斯康辛结石生活质量问卷(WISQOL)评分对比评价两组患者术后生活质量。结果:两组患者术中手术时间、出血量比较,差异均无统计学意义(P>0.05),观察组术后住院时间为(2.28±0.49)d,短于对照组(3.10±0.54)d,差异有统计学意义(t=3.464,P<0.05)。观察组结石清除效果中一次性碎石成功率和30 d结石清除率高于对照组,结石上移率低于对照组,差异有统计学意义(x^(2)=6.698、7.240、5.489,P<0.05)。观察组患者术后血清肌酐(Scr)、血尿素氮(BUN)和尿微量白蛋白(MAU)较对照组有显著下降,差异有统计学意义(t=6.320、8.115、9.231,P<0.05)。观察组术后3、6、12个月时的肾积水程度较对照组有明显缓解,差异有统计学意义(t=3.218、3.345、2.985,P<0.05)。观察组术后6、12个月时复发率均低于对照组,差异有统计学意义(x^(2)=5.114、5.783,P<0.05)。观察组术后并发症发生率低于对照组,差异有统计学意义(x^(2)=4.865,P<0.05)。观察组术后WISQOL评分各维度总分及精力、睡眠状况、躯体症状、总体情绪总分均高于对照组,差异有统计学意义(t=3.734、3.889、3.903、4.340、4.650,P<0.05)。结论:输尿管镜钬激光碎石术联合N-trap拦截网篮治疗中上段输尿管结石能够有效提高结石清除率,缩短术后住院时间,降低术后并发症发生率和复发率,促进肾功能恢复,提高患者术后生�Objective:To study the clinically curative effect of ureteroscopic holmium laser lithotripsy combined with intercepted basket of capture and extraction device for stone(N-trap)in treating middle and upper ureteral stones.Methods:A total of 112 patients with middle and upper ureteral stone who were diagnosed and treated in the Department of Urology of the Second Affiliated Hospital of Wannan Medical College from September 2020 to September 2022 were prospectively selected as the study subjects,and they were divided into two groups according to the random number table method,with 56 cases in each group.The control group was treated with ureteroscopic holmium laser lithotripsy alone,and the observation group was treated with ureteroscopic holmium laser lithotripsy combined with N-trap intercepted basket for treatment.The related indicators of surgery,the stone removal effect,renal function indicators,postoperative renal mass,postoperative recurrence and postoperative complications between two groups were compared.The scores of the Wisconsin Stone Quality of Life(WISQOL)questionnaire were used to compare and evaluate the postoperative quality of life between the two groups.Results:There were no significant differences in intraoperative operation time and intraoperative blood loss between the two groups(P>0.05),and the postoperative hospitalization time in the observation group was significantly shorter than that in the control group(t=3.464,P<0.05).The success rate of one-time lithotripsy and the clearance rate of stone within 30 d in the observation group were significantly higher than those in the control group,and the upward movement rate of stones of the observation group was significantly lower than that in the control group,and the difference was statistically significant(x^(2)=6.698,7.240,5.489,P<0.05),respectively.The postoperative serum creatinine(Scr),blood urea nitrogen(BUN)and urine microalbumin(UMA)in the observation group were significantly lower than those in the control group,and the differences were

关 键 词：N-trap拦截网篮 输尿管结石 钬激光碎石术 肾功能 生活质量 

分 类 号：R693[医药卫生—泌尿科学]