腹腔镜手术与开腹手术治疗胃肠道穿孔的疗效研究  

Effect of Laparoscopic and Open Surgery on Gastrointestinal Perforation

作　　者：吴海彪 何亦工 何龙贵 WU Haibiao;HE Yigong;HE Longgui(Department of General Surgery,Wuyishan Municipal Hospital,Wuyishan,Fujian Province,354300 China)

机构地区：[1]福建省武夷山市立医院普外科,福建武夷山354300

出　　处：《中外医疗》2024年第10期50-53,共4页China & Foreign Medical Treatment

摘　　要：目的分析腹腔镜手术治疗胃肠道穿孔的效果。方法方便选取2021年5月—2023年12月武夷山市立医院收治的98例胃肠道穿孔患者,根据密闭信封法分为对照组(n=49)、研究组(n=49)。对照组行开腹手术治疗,研究组实施腹腔镜手术。对比两组手术指标,术前及术后1 d超敏C反应蛋白(High-sensitivity C-reactive Protein,hs-CRP)、肿瘤坏死因子-α(Tumor Necrosis Factor Alpha,TNF-α)及白细胞介素6(Interleukin-6,IL-6)水平,对比肠粘连、腹腔感染、切口感染发生率,对比术前及术后1个月生活质量简表(World Health Organization Quality of Life-100,WHOQOL-100)评分。结果研究组各项手术指标均优于对照组,差异有统计学意义(P均<0.001);术后1 d,研究组hs-CRP、TNF-α、IL-6水平均低于对照组,差异有统计学意义(P均<0.001);研究组并发症发生率为2.04%,低于对照组的14.29%,差异有统计学意义(χ^(2)=4.900,P=0.027);术后1个月,研究组WHOQOL-100评分高于对照组,差异有统计学意义(P<0.05)。结论腹腔镜手术治疗胃肠道穿孔效果较优,能够改善炎症指标水平,降低并发症风险,促进术后康复,提高患者生活质量。Objective To analyze the effect of laparoscopic surgery on gastrointestinal perforation.Methods A total of 98 patients with gastrointestinal perforation admitted to Wuyishan Municipal Hospital from May 2021 to December 2023 were conveniently selected and divided into control group(n=49)and study group(n=49)according to sealed envelope method.The control group underwent open surgery,and the study group underwent laparoscopic surgery.The surgical indicators and levels of high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor alpha(TNF-α)and interleukin-6(IL-6)in the two groups before and one day after surgery were compared between two groups.The incidence of intestinal adhesion,abdominal infection and incision infection was compared.The World Health Organization Quality of Life-100(WHOQOL-100)scores were compared before and one month after surgery.Results All surgical indicators in the study group were better than those in the control group,the differences were statistically significant(all P<0.001).The levels of hs-CRP,TNF-α and IL-6 in the study group were lower than those in the control group one day after surgery,the differences were statistically significant(all P<0.001).The complication rate of the study group was 2.04%,which was lower than that of the control group 14.29%,the difference was statistically significant(χ^(2)=4.900,P=0.027).One month after operation,the WHOQOL-100 score of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery is effective in the treatment of gastrointestinal perforation,which can improve the level of inflammation indicators,reduce the risk of complications,promote postoperative rehabilitation and improve the quality of life of patients.

关 键 词：腹腔镜 开腹手术 胃肠道穿孔 机体损伤 炎症指标 生活质量 

分 类 号：R4[医药卫生—临床医学]