米非司酮配伍米索前列醇治疗稽留流产的效果  

Effect of mifepristone combined with misoprostol in the treatment of missed abortion

作　　者：李慧芬 Li Huifen(Department of Obstetrics and Gynecology,The Sixth People's Hospital of Nantong,Nantong 226001,China)

机构地区：[1]南通市第六人民医院妇产科,江苏南通226001

出　　处：《实用妇科内分泌电子杂志》2024年第6期39-41,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究米非司酮联合米索前列醇治疗稽留流产的效果。方法选择100例发生稽留流产的孕妇为研究对象,使用随机数字法将其分为对照组、研究组,每组50例。对照组采用100mg米非司酮顿服联合0.6mg米索前列醇治疗,研究组采用200mg米非司酮(分2d口服)联合0.6mg米索前列醇治疗。比较两组孕妇的人绒毛膜促性腺激素(HCG)水平恢复正常时间及稽留流产治疗成功率。结果研究组治疗成功率为84.00%,高于对照组的66.00%,差异有统计学意义(P<0.05)。研究组HCG水平恢复正常时间为(23.62±1.47)d,短于对照组的(25.03±1.54)d,差异有统计学意义(P<0.05)。结论分2d口服200mg米非司酮配伍米索前列醇治疗,能有效提高稽留流产治疗成功率,缩短HCG恢复时间。Objective To investigate the effect of mifepristone combined with misoprostol in the treatment of missed abortion.Methods 100 pregnant women with missed abortion were selected as the study objects and were divided into a control group and a study group by random number method,with 50 cases in each group.The control group was treated with 100 mg mifepristone combined with 0.6 mg misoprostol,and the study group was treated with 200 mg mifepristone(orally divided into 2 days)combined with 0.6 mg misoprostol.The normal time of human chorionic gonadotropin(HCG)level and the success rate of missed abortion treatment were compared between the two groups.Results The success rate of treatment in the study group was 84.00%,which was higher than 66.00% in the control group,the difference was statistically significant(P<0.05).The recovery time of HCG level in the study group was(23.62±1.47)d,which was shorter than(25.03±1.54)d in the control group,and the difference was statistically significant(P<0.05).Conclusion 200 mg oral mifepristone in 2 days combined with misoprostol can effectively improve the success rate of missed abortion treatment and shorten the recovery time of HCG.

关 键 词：米非司酮 米索前列醇 稽留流产 

分 类 号：R714.21[医药卫生—妇产科学]