孕早期检测NLR、氧化应激指标对妊娠期糖尿病的预测价值  

The predictive value of NLR and oxidative stress indexes in early pregnancy on gestational diabetes

作　　者：陈玉兰 曾贵红 Chen Yulan;Zeng Guihong(Department of Obstetrics,Fuyong People's Hospital,Bao'an District,Shenzhen 518000,China)

机构地区：[1]深圳市宝安区福永人民医院产科,广东深圳518000

出　　处：《实用妇科内分泌电子杂志》2024年第9期32-34,41,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨孕早期检测中性粒细胞/淋巴细胞(NLR)、氧化应激指标对妊娠期糖尿病的预测价值。方法选取本院33例妊娠期糖尿病孕妇(探讨组)和33例正常孕妇(对照组)为研究对象,比较两组的血化验指标、氧化应激指标及不良妊娠结局发生率。结果探讨组活性氧水平高于对照组,核转录因子E_(2)相关因子水平低于对照组,差异有统计学意义(P<0.05);探讨组的不良妊娠结局发生率为33.33%,高于对照组的12.12%,差异有统计学意义(P<0.05);探讨组白细胞计数、NLR、丙氨酸转氨酶水平高于对照组,差异有统计学意义(P<0.05)。结论孕早期检测NLR、氧化应激指标对妊娠期糖尿病有一定的预测价值,能尽早分析疾病,从而尽早开始治疗。Objective To explore the predictive value of neutrophil/lymphocyte(NLR)and oxidative stress indicators in early pregnancy for gestational diabetes.Methods 33 pregnant women with gestational diabetes(study group)and 33 normal pregnant women(control group)in our hospital were selected as research objects.Compare the blood test indicators,oxidative stress indicators,and incidence of adverse pregnancy outcomes between two groups.Results The levels of reactive oxygen species in the exploration group were higher than those in the control group,and the levels of nuclear transcription factor E_(2) related factors were lower than those in the control group,with statistical significance(P<0.05);The incidence of adverse pregnancy outcomes in the exploration group was 33.33%,higher than the control group's 12.12%,and the difference was statistically significant(P<0.05);The white blood cell count,NLR,and alanine aminotransferase levels in the exploration group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The detection of NLR and oxidative stress indicators in early pregnancy has certain predictive value for gestational diabetes,which can analyze the disease as soon as possible,so as to start treatment as soon as possible.

关 键 词：氧化应激指标 妊娠期糖尿病 孕早期 血化验指标 不良妊娠结局发生率 

分 类 号：R714.256[医药卫生—妇产科学]