个性化医学营养疗法联合二甲双胍治疗妊娠期 糖尿病患者的疗效探讨  

Clinical efficacy of personalized medicine nutrition therapy combined with metformin in the treatment of gestational diabetes mellitus

作　　者：郝菲 杨莹 刘敏 Hao Fei;Yang Ying;Liu Min(Department of Endocrinology,Jiaozhou Central Hospital,Qingdao 266300,China;Department of Cardiology,Jiaozhou Central Hospital,Qingdao 266300,China)

机构地区：[1]山东省青岛市胶州中心医院内分泌科,山东青岛266300 [2]山东省青岛市胶州中心医院心内科,山东青岛266300

出　　处：《实用妇科内分泌电子杂志》2024年第9期57-59,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究个性化医学营养疗法联合二甲双胍治疗妊娠期糖尿病患者的临床疗效。方法选取96例妊娠期糖尿病患者,利用随机抽签法分组,每组48例。对照组予以个性化医学营养疗法,观察组在对照组基础上联合二甲双胍。比较两组血糖水平和不良妊娠结局发生率。结果干预后观察组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均明显低于对照组(P<0.05)。观察组新生儿低血糖率4.17%、早产率6.25%、剖宫产率18.75%均明显低于对照组的16.67%、20.83%、37.50%(P<0.05)。结论妊娠期糖尿病患者予以个性化医学营养疗法联合二甲双胍治疗可更有效控制血糖水平,降低不良妊娠结局发生率,具有临床推广价值。Objective To explore the clinical efficacy of personalized medicine nutrition therapy combined with metformin in the treatment of gestational diabetes mellitus.Methods 96 patients with gestational diabetes mellitus were selected and divided into 48 cases in each group by random drawing method.The control group was given personalized medicine nutrition therapy,and the observation group was combined with metformin on the basis of the control group.Blood glucose levels and incidence of adverse pregnancy outcomes were compared between the two groups.Results After intervention,the levels of fasting blood glucose,2 h postprandial blood glucose and HBAlc in the observation group were significantly lower than those in the control group(P<0.05).The neonatal hypoglycemia rate of 4.17%,premature delivery rate of 6.25%and cesarean section rate of 18.75%in the observation group were significantly lower than those in the control group16.67%,20.83%and 37.50%(P<0.05).Conclusion Personalized medicine nutrition therapy combined with metformin can more effectively control blood glucose level and reduce the incidence of adverse pregnancy outcomes in patients with gestational diabetes,which has clinical promotion value.

关 键 词：妊娠期糖尿病 个性化医学营养疗法 二甲双胍 

分 类 号：R714.256[医药卫生—妇产科学]