降钙素原的检测及在外科手术后感染判断中的应用  

Detection of Procalcitonin and its Application in the Judgment of Infection After Surgery

作　　者：于永亮 蔡澄涵 姜凤全 YU Yong-liang;CAI Cheng-han;JIANG Feng-quan(Department of Clinical Laboratory,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,Liaoning,China;College of Medical Laboratory,Dalian Medical University,Dalian 116011,Liaoning,China)

机构地区：[1]大连医科大学附属第一医院检验科,辽宁大连116011 [2]大连医科大学检验医学院,辽宁大连116011

出　　处：《医学信息》2024年第11期189-192,共4页Journal of Medical Information

摘　　要：降钙素原(PCT)是一类无激素活性的降钙素前体物质,可以通过神经内分泌细胞释放,并在蛋白酶的影响下形成活性成分,目前已普遍应用于临床手术术后感染评估。正常情况下,PCT仅会少量进入血液,可用于鉴别诊断感染的病原微生物的类型及感染的程度,同时可以更好地监测患者的感染病情变化,并指导抗生素的使用。近年来越来越多的外科医生也将PCT用于手术后的感染评估。本文将围绕PCT的生物学特性、方法及其在外科手术后的应用进行综述,旨在为PCT在外科术后应用提供参考。Procalcitonin(PCT)is a class of non hormonal active calcitonin precursors that can be released by neuroendocrine cells and form active components under the influence of proteases.Currently,it has been widely used in the evaluation of postoperative infection in clinical surgery.Under normal circumstances,PCT only enters the blood in a small amount.PCT can be used to identify and diagnose the type and degree of infection of pathogenic microorganisms.It can also help doctors better monitor the changes in patients'infection conditions and guide the use of antibiotics.In recent years,more and more surgeons have also used PCT for postoperative infection evaluation.This article will focus on the biological characteristics,methods and application of procalcitonin PCT after surgery,aiming to provide reference for the application of PCT after surgery.

关 键 词：降钙素原 外科手术 术后感染 

分 类 号：R446[医药卫生—诊断学]