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作 者:李静[1] 曹兰秀[1] 郑文 LI Jing;CAO Lanxiu;ZHENG Wen(Shaanxi University of Chinese medicine,Xianyang Shaanxi China 712046)
出 处:《中医学报》2024年第6期1214-1219,共6页Acta Chinese Medicine
基 金:咸阳市科学技术局课题项目(2021ZDYF-SF-0002)。
摘 要:白芍,始载于《神农本草经》,具有悠久的应用历史,其性味功效明确,临床应用广泛。白芍中化学成分丰富,含有单萜及其苷类、三萜及其苷类、黄酮类、鞣质类以及多糖类化合物,具有抗炎、抗抑郁、镇痛、促进造血功能、调节免疫等药理作用。白芍配伍桂枝可调和阴阳,对心血管系统疾病的防治起到重要作用;配伍柴胡可增强疏肝解郁之力,对治疗神经系统疾病效果显著;配伍当归可活血止痛,对痛经治疗效果明显;配伍甘草可缓急止痛,可用于治疗各个系统的痛症;配伍白术可健脾止泻,对治疗溃疡性结肠炎作用明显;配伍枳实可行气消胀,对胃肠功能具有双向调节作用。配伍后的药对功效比单味药疗效更强,临床应用范围更加广泛,对于指导临床用药思路及处方具有重要意义。Baishao(Paeonia Radix Alba),which was first recorded in the Shen Nong Ben Cao Jing,has a long history of clinical application.It is widely used in TCM clinical practice with its specific nature,flavor and effects.In modern pharmacology it is found that there are abundant chemical components in Baishao(Paeonia Radix Alba),including monoterpenes and their glycosides,triterpenes and their glycosides,flavonoids,tannins as well as polysaccharides.Baishao(Paeonia Radix Alba)has multiple pharmacological effects such as anti-inflammatory,antidepressant,analgesic,promoting hematopoietic function and regulating immunity.The drug pair of Baishao-Guizhi(Paeonia Radix Alba-Ramulus Cinnamomi)can regulate Yin and Yang and play an important role in prevention and treatment of cardiovascular diseases;Baishao-Chaihu(Paeonia Radix Alba-Bupleuri Radix)can enhance the power of soothing the Liver and relieving depression and has a significant effect on the treatment of nervous system diseases;Baishao-Danggui(Paeonia Radix Alba-Angelicae Sinensis Radix)can promote blood circulation and relieve pain,and has obvious therapeutic effect on dysmenorrhea;Baishao-Gancao(Paeonia Radix Alba-Glycyrrhizae Radix et Rhizoma)can relieve spasm to stop pain,and can be used to treat pain of various systems;Baishao-Baizhu(Paeonia Radix Alba-Atractylodis Macrocephalae Rhizoma)can invigorate Spleen and stop diarrhea,and has obvious effect on ulcerative colitis;Baishao-Zhishi(paeonia Radix Alba-Aurantii Fructus Immaturus)can moving Qi to disperse flatulence,and has two-way regulating effect on gastrointestinal function.The efficacy of the compatible drug pairs above is stronger than that of the single drug,and the clinical application range is wider,which is of great significance for guiding clinical medication and prescription.
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