麻醉精准干预在高危心血管病患者非心脏手术围手术期的应用效果  

Application effect of precision anesthesia intervention in non-cardiac surgery perioperative period in high-risk cardiovascular patients

作　　者：张莉[1] 王义[1] 曾恒 翟浩宇 ZHANG Li;WANG Yi;ZENG Heng;ZHAI Haoyu(Department of Anesthesiology,the First People's Hospital of Guangyuan,Sichuan Province,Guangyuan628017,China)

机构地区：[1]四川省广元市第一人民医院麻醉科,四川广元628017

出　　处：《中国当代医药》2024年第14期59-62,共4页China Modern Medicine

基　　金：四川省广元市科技计划项目(22ZDYF0038)。

摘　　要：目的探讨麻醉精准干预在高危心血管病患者非心脏手术围手术期的应用效果。方法选取2022年1月至12月四川省广元市第一人民医院收治的190例高危心血管病患者作为研究对象,按照随机数字表法分为观察组(95例)与对照组(95例),对照组采用普通经验管理,观察组采用麻醉精准干预措施,比较两组患者的血清学指标和心脏不良事件发生率。结果术后观察组肌钙蛋白(cTn)、肌酸激酶同工酶(CK-MB)、肌红蛋白(Mb)、高敏肌钙蛋白T(hs-TnT)、脑钠肽(BNP)、氨基末端脑钠肽前体(NT-proBNP)、C反应蛋白(CRP)均低于对照组,差异有统计学意义(P<0.05)。观察组心脏不良事件总发生率低于对照组,差异有统计学意义(P<0.05)。结论麻醉精准干预应用于高危心血管患者非心脏手术围手术期能进一步减轻对心脏损伤,且降低不良事件发生率,值得临床应用。Objective To investigate the effect of precision anesthesia intervention in non-cardiac surgery perioperative period in high-risk cardiovascular patients.Methods A total of 190 high-risk cardiovascular patients admitted to the First People's Hospital of Guangyuan from January to December 2022 were selected as research objects,and they were divided into observation group(95 cases)and control group(95 cases)according to random number table method.The control group was administered with general experience management,and the observation group was administered with precision anesthesia intervention measures.Serological indexes and incidence of cardiac adverse events were compared between the two groups.Results Cardiac troponin(cTn),creatine kinase isoenzyme(CK-MB),myoglobin(Mb),high sensitivity troponin T(hs-TnT),brain natriuretic peptide(BNP),N terminal pro B type natriuretic peptide(NT-proBNP)and C-reactive protein(CRP)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The total incidence of cardiac adverse events in observation group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion Precision anesthesia intervention in high-risk cardiovascular patients during non-cardiac surgery perioperative period can further reduce cardiac injury and reduce the incidence of adverse events,which is worthy of clinical application.

关 键 词：高危心血管病 非心脏手术 围手术期 麻醉精准干预 心脏不良事件 

分 类 号：R614[医药卫生—麻醉学]