三白草地下部分化学成分研究  

Chemical Constituents from the Underground Parts of Saururus chinensis

作　　者：高秀 徐晴芳 张丽芳 刘威良 蔡建 GAO Xiu;XU Qing-fang;ZHANG Li-fang;LIU Wei-liang;CAI Jian(College of Biological Resources and Food Engineering,Qujing Normal University/Yunnan University Characteristic Fruit Wine Tech-nology Innovation and Application Engineering Research Center,Qujing 655011,China)

机构地区：[1]曲靖师范学院生物资源与食品工程学院/云南省高校特色果酒技术创新与应用工程研究中心,云南曲靖655011

出　　处：《中药材》2024年第1期102-105,共4页Journal of Chinese Medicinal Materials

基　　金：云南省科技厅-云南省地方本科高校基础研究联合专项项目(2017FH001-094);地方高校国家级大学生创新创业训练计划项目(201610684010)。

摘　　要：目的:研究三白草科三白草属植物三白草Saururus chinensis(Lour.) Baill.地下部分的化学成分。方法:采用MCI、硅胶、Sephadex LH-20葡聚糖凝胶等多种色谱技术对三白草地下部分的丙酮提取物进行分离纯化,根据波谱数据鉴定所得化合物的结构。结果:从三白草地下部分中分离得到13个化合物,分别鉴定为:ent-4β-hydroxy-10α-ethoxyaromadendrane(1)、ent-4α-hydroxy-10β-alloaromadendranediol-10-monomethylether(2)、4β-10α-香木兰烷二醇(3)、斯巴醇(4)、meicocarpin(5)、1,4-二(3,4-二甲氧基苯基)-2,3-二甲基-1,4-丁二酮(6)、乙酰樟叶素(7)、(-)-(7R,8R)-7-O-acetylraphidecursinol B(8)、赤式-2-(4-烯丙基-2,6-二甲氧基苯氧基)-1-(3,4,5-三甲氧基苯基)-丙烷-1-醇(9)、saururin C(10)、(-)-5-exo-acefoxybornyl acetate(11)、细辛醚(12)、榄香脂素(13)。结论:其中,化合物1~4、9、11为首次从该植物中分离得到。Objective:To study the chemical constituents from the underground parts of Saururus chinensis.Methods:The acetone extract of the underground parts of Saururus chinensis were isolated and purified by column chromatography on MCI,silica gel,Sephadex LH-20,the structures of obtained compounds were identified on the basis of spectroscopic data.Results:Thirteen compounds were isolated from the underground parts of Saururus chinensis and identified as ent-4β-hydroxy-10α-ethoxyaromadendrane(1),ent-4α-hydroxy-10β-alloaromadendranediol-10-monomethylether(2),4β-10α-aromadendranediol(3),spathulenol(4),meicocarpin(5),1,4-bis(3,4-dimethyoxyphenyl)-2,3-dimethyl-1,4-butanedione(6),acetylpolysyphorin(7),(-)-(7R,8R)-7-O-acetylraphidecursinol B(8),erythro-2-(4-allyl-2,6-dimethoxyphenoxy)-1-(3,4,5-trimethoxyphenyl)-propan-1-ol(9),saururin C(10),(-)-5-exo-acefoxybornyl acetate(11),sarisan(12),elemicin(13),respectively.Conclusion:Among them,compounds 1 to 4,9,11 are isolated from Saururus chinensis for the first time.

关 键 词：三白草地下部分 化学成分 木脂素 倍半萜 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]