还阳通络灸在原发性肝癌介入治疗中的临床应用研究  

Clinical application of Huanyang Tongluo moxibustion in interventional therapy of primary hepatic carcinoma

作　　者：鲍乐[1] 刘颖 王友彬[1,3] 陈龙 朱玉芝[4] 梁爽 权鹤太 李鹏飞[1] Bao Le;Liu Ying;Wang Youbin;Chen Long;Zhu Yuzhi;Liang Shuang;Quan Hetai;Li Pengfei(Department of Interention,Xuzhou Cancer Hospital,Xuzhou 221000,China;Department of Acupuncture,Xuzhou Cancer Hospital,Xuzhou 221000,China;Department of Medical Service,Xuzhou Cancer Hospital,Xuzhou 221000,China;Department of Information,Xuzhou Cancer Hospital,Xuzhou 221000,China)

机构地区：[1]徐州市肿瘤医院介入科,江苏省221000 [2]徐州市肿瘤医院中医针灸科,江苏省221000 [3]徐州市肿瘤医院医务处,江苏省221000 [4]徐州市肿瘤医院信息处,江苏省221000

出　　处：《中华消化病与影像杂志（电子版）》2024年第3期197-202,共6页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

基　　金：徐州市重点研发计划(社会发展)-医药卫生面上项目(KC22150)。

摘　　要：目的分析还阳通络灸在原发性肝癌介入治疗中的临床应用效果与安全性。方法纳入2021年6月至2023年6月徐州市肿瘤医院收治的80例原发性肝癌患者,使用简单随机法分别纳入观察组(n=40)、对照组(n=40),2组均行肝动脉插管化疗栓塞术(TACE)治疗,观察组加用还阳通络灸。对比2组治疗前后疼痛视觉模拟评分(VAS)、血清β-内啡肽(β-EP)、5-羟色胺(5-HT)和卡氏功能状态评分(KPS)、肿瘤患者生活质量核心量表(EORTCQLQ-C30)评分变化,并比较2组中医临床疗效和恶心呕吐发生情况。结果2组治疗1、3个月后VAS评分、β-EP均较治疗前下降(P<0.05),5-HT、KPS评分、EORTCQLQ-C30评分均较治疗前升高(P<0.05);且治疗后观察组VAS评分、β-EP均低于对照组(P<0.05),5-HT、KPS评分、EORTC QLQ-C30评分均高于对照组(P<0.05)。治疗3个月后,观察组总有效率82.50%较对照组60.00%更高(P<0.05);TACE术后6h和24h,观察组恶心呕吐发生率及严重程度均较对照组更低(P<0.05)。结论还阳通络灸能够有效减轻原发性肝癌患者躯体疼痛、改善应激和情绪功能、提高活动能力和生活质量,并且对于增强TACE治疗效果、降低TACE恶心呕吐可能有益。Objective To analyze the clinical application effect and safety of Huanyang Tongluo moxibustion in interventional therapy of liver cancer.Methods Eighty patients with liver cancer admitted to Xuzhou Cancer Hospital from June 2021 to June 2023 were randomly divided into the observation group(n=40)and the control group(n=40).Both groups were treated by transcatheter hepatic arterial chemoembolization(TACE),and the observation group was treated with Huanyang Tongluo moxibustion.The changes of pain visual analogue scale(VAS),serumβ-endorphin(β-EP),5-hydroxytryptamine(5-HT),Karnofsky performance status(KPS)score and core quality of life scale for cancer patients(EORTC QLQC30)were compared between the two groups before and after treatment,and the clinical efficacy and nausea and vomiting occurrence of the two groups were compared.Results After one month and three months of treatment,the VAS score andβ-EP of the two groups decreased(P<0.05),while the 5-HT score,KPS score and EORTC QLQ-C30 score increased(P<0.05).The VAS score andβ-EP in the observation group after treatment were lower than those in the control group(P<0.05),while the 5-HT score,KPS score and EORTC QLQ-C30 score were higher than those in the control group(P<0.05).After 3 months of treatment,the total effective rate of the observation group was higher than that of the control group(82.50%vs.60.00%,P<0.05).During the treatment period,the incidence and severity of nausea and vomiting in the observation group were lower than those in the control group(P<0.05).Conclusion Huanyang Tongluo moxibustion can effectively relieve patients'physical pain,improve stress and emotional function,improve activity ability and quality of life,and may be beneficial to enhance the therapeutic effect of TACE and reduce nausea and vomiting of TACE.

关 键 词：原发性肝癌 肝动脉插管化疗栓塞术 还阳通络灸 安全性 

分 类 号：R273[医药卫生—中西医结合]