生物标志物在结核病诊断中的研究进展  

Advances in biomarker research for tuberculosis diagnosis

作　　者：徐文辉 张艳秋[2] 石洁[2] 孙定勇 Xu Wenhui;Zhang Yanqiu;Shi Jie;Sun Dingyong(Department of Epidemiology,School of Public Health,Zhengzhou University,Zhengzhou 450001,China;Department of Tuberculosis Prevention and Control Center,Henan Center for Disease Control and Prevention,Zhengzhou 450016,China)

机构地区：[1]郑州大学公共卫生学院流行病学系,郑州450001 [2]河南省疾病预防控制中心结核病预防控制所,郑州450016

出　　处：《中国防痨杂志》2024年第6期713-721,共9页Chinese Journal of Antituberculosis

基　　金：河南省科技发展计划(212102310156);河南省医学科技攻关计划联合共建项目(LHGJ20210136)。

摘　　要：结核病是全球性的公共卫生问题,结核分枝杆菌生物标志物可以用于结核病的早期诊断和治疗监测。但现有结核病诊断方法存在不足,亟需寻找新的易获取的快速诊断结核病的生物标志物,以探索快速诊断结核病的新方法。本综述介绍了来源于血液、尿液、唾液及其他样本的结核病生物标志物最新研究进展,为开发新型结核病诊断方法提供线索。Tuberculosis is a global public health problem.Biomarkers of Mycobacterium tuberculosis can be used for early diagnosis and treatment monitoring of tuberculosis.However,current tuberculosis diagnostic methods are insufficient,and there is an urgent need to identify new and easily accessible biomarkers for rapid diagnosis of tuberculosis to explore new methods for rapid diagnosis of tuberculosis.This review introduces the latest research progress of tuberculosis biomarkers in blood,urine,saliva and other sample sources,respectively,to provide clues for the development of novel tuberculosis diagnostic methods.

关 键 词：结核 生物因子 生物学标记 诊断 综述文献(主题) 

分 类 号：R52[医药卫生—内科学]