嘌呤信号:中医药研究新靶点  

Purinergic Signaling:New Target for Traditional Chinese Medicine

作　　者：尹海燕[1,2] Patrizia Rubini Peter Illes 唐勇 Yin Haiyan;Patrizia Rubini;Peter Illes;Tang Yong(School of Acupuncture and Tuina,Chengdu University of Traditional Chinese Medicine,Chengdu,611137,China;International Joint Research Centre on Purinergic Signalling,Chengdu,611137,China;Medical school,University of Leipzig,Leipzig,04107,Germany;School of and Health and Rehabilitation,Chengdu University of Traditional Chinese Medicine,Chengdu,611137,China)

机构地区：[1]成都中医药大学针灸推拿学院,四川成都611137 [2]嘌呤信号国际联合研究中心,四川成都611137 [3]莱比锡大学医学院,德国莱比锡04107 [4]成都中医药大学养生康复学院,四川成都611137

出　　处：《成都中医药大学学报》2024年第3期1-7,共7页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家自然科学基金(81774437,82274668);中德科学中心(GZ919,M0679)。

摘　　要：嘌呤信号主要包括三磷酸腺苷(Adenosine Triphosphate,ATP)、二磷酸腺苷(Adenosine Diphosphate,ADP)、一磷酸腺苷(Adenosine Monophosphate,AMP)和腺苷(Adenosine,ADO)4类物质、CD39和CD73两种酶以及19种嘌呤受体(P1、P2X、P2Y),与机体各个系统均有密切关系。本文主要指出目前嘌呤信号的研究重点和中医药的未来结合靶点。Purinergic signaling consists of 4 purines(ATP,ADP,AMP,and ADO),2 main enzyme(CD39,Cd73),and 19 purinergic receptors(P1,P2X,and P2Y),which was clearly associated with every system of the whole body.In this review,we mainly pointed out the state-of-the-art situation and try to forecast how the field is likely to develop in traditional Chinese medicine in the future.

关 键 词：嘌呤信号 中医药 靶点 

分 类 号：R2[医药卫生—中医学] R45