针灸治疗慢性阻塞性肺疾病临床研究证据图分析  

Evidence Maping of Acupuncture for Chronic Obstructive Pulmonary Disease

作　　者：余欣 徐桂兴 田昊 陈明 李茜 孙铭声 余曙光[1] 杨莎[1,3] Yu Xin;Xu Guixing;Tian Hao;Chen Ming;Li Qian;Sun Mingsheng;Yu Shuguang;Yang Sha(Acupuncture and Tuina School,Chengdu University of Traditional Chinese Medicine,610075,Chengdu,China;Clinical Research Center for Acupuncture and Moxibustion in Sichuan Province,610075,Chengdu,China;Acupuncture-Brain Science Research Center,Chengdu University of Traditional Chinese Medicine,610075,Chengdu,China)

机构地区：[1]成都中医药大学针灸推拿学院,四川成都610075 [2]四川省针灸临床研究中心,四川成都610000 [3]成都中医药大学针灸脑科学研究中心,四川成都610075

出　　处：《成都中医药大学学报》2024年第3期65-73,共9页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-D-202003)。

摘　　要：目的:本研究旨在通过证据图的方法,整理针刺治疗慢性阻塞性肺疾病的临床研究,探讨慢性阻塞性肺疾病的现状。方法:计算机检索中国知网(CNKI)、万方数据知识服务平台(WanFang Data)、维普中文期刊服务平台(VIP)、中国生物医学文献服务系统(CBM)、PubMed、Cochrane Library、EMBASE、Ovid web数据库中针灸治疗慢性阻塞性肺疾病文献,检索时间为建库至2022年3月2日。分析方法质量学评价、研究总体趋势、样本量、干预措施设计、疗效评价指标。方法学质量评价采用AMSTAR-2工具,并对纳入的干预性研究以图表和文字结合的形式总结证据特点。结果:共纳入干预性研究637篇,系统评价20篇。研究总体成上升趋势且近年有所增长;研究干预措施单一疗法为371篇(58%)占多半,又以穴位贴敷203篇(55%)居多,双臂试验为主;肺功能检查、有效率、急性加重次数是现有针灸治疗COPD临床研究关注较多的结局指标,同时高质量的系统评价较少。结论:针灸治疗COPD具有优势性。干预措施和疗效评价指标具有多样性,但合理性需要优化,结局指标尚需优化选择;今后需进一步扩大研究以及提高相关系统评价/Meta分析的方法学质量,完善研究设计和研究方案,为证据使用者和相关领域研究的进一步优化提供证据支撑。Objective The purpose of this study is to arrange the clinical studies of acupuncture for chronic obstructive pulmonary disease by utilizing the evidence map method,in order to analyze the current situation of chronic obstructive pulmonary disease.Methods The databases CNKI,WanFang Data,VIP,CBM,PubMed,Cochrane Library,EMBASE and Ovid web were searched on related articles about chronic obstructive pulmonary disease treated by acupuncture-moxibustion,from initiation to March 2,2022.The analysis was conducted in terms of methodological qualitative evaluation,general trends in studies,sample size,intervention design,efficacy evaluation indicators.This paper summarizes the evidence characteristics of the primary studies in the form of the combination of the graphs and the descriptions,meanwhile evaluates the quality of the methodology of the systematic reviews(SR)/Meta-analysis via AMSTAR-2 tool.Results A total of 637 interventional studies and 20 systematic reviews were included.The overall trend of research is rising and has increased in recent years;research interventions monotherapy for 371(58%)accounted for more than half of the articles,but also to the acupoints paste 203(55%)most of the articles,the two-armed test is dominant;pulmonary function tests,efficiency,acute exacerbation number is the existing acupuncture treatment of COPD clinical research focus more on the outcome indicators,while the high quality of systematic evaluation is less.Conclusion Acupuncture has superiority in treating COPD.Its interventions and efficacy evaluation indexes have diversity,but their rationality needs to be optimized,and the outcome indexes still need to be optimized and selected;in the future,it is necessary to further expand the studies as well as improve the methodological quality of related systematic evaluations/Meta-analyses,and improve the study design and study protocols,so as to provide evidence support for the further optimization of the research for evidence users and the related fields.

关 键 词：针灸 慢性阻塞性肺疾病 临床研究 证据图 AMSTAR-2 

分 类 号：R245[医药卫生—针灸推拿学] R256.1[医药卫生—中医临床基础]