神经内镜小切口锁孔手术治疗脑转移瘤的应用研究  

Application study of neuroendoscopic small incision keyhole surgery for brain metastases

作　　者：费小斌[1] 朱池豪 陈昕 周至宜 王冉[2] 程丽霖 邱永明[2] 缪亦锋[2] Fei Xiaobin;Zhu Chihao;Chen Xin;Zhou Zhiyi;Wang Ran;Cheng Lilin;Qiu Yongming;Miao Yifeng(Department of Neurosurgery,Jiangyin Hospital of Southeast University,Jiangyin 214433,China;Department of Neurosurgery,South Hospital of Renji Hospital,Medical College in Shanghai Jiaotong University,Shanghai 200127,China)

机构地区：[1]东南大学医学院附属江阴医院神经外科,214433 [2]上海交通大学医学院附属仁济医院南院神经外科,200127

出　　处：《中华转移性肿瘤杂志》2021年第3期195-198,共4页Chinese Journal of Metastatic Cancer

摘　　要：目的分析神经内镜小切口锁孔入路治疗脑转移瘤的手术方式,探讨其临床应用价值。方法选择我院2016—2019年间连续收治的共72例脑转移瘤患者作为研究对象,随机分组为对照组和观察组各36例。对照组采用常规显微镜手术方式,观察组采用神经内镜小切口锁孔入路方式,对照两组手术时间、出院时间、并发症发生率。应用KPS生存质量评分评估术后随访情况并进行对比分析。结果观察组平均手术时间为(1.8±0.6)h,平均出院时间为(6.3±1.7)d,并发症发生率为13%(4/32);对照组平均手术时间为(2.9±1.3)h,平均出院时间为(9.6±1.5)d,并发症发生率为28%(9/32);两组对比差异统计学意义(均P<0.05)。观察组术后1个月、半年的KPS评分分别为91.1±3.6、78.8±6.2,对照组的分别为82.8±5.3、75.2±4.5,两组对比术后1个月生存质量不同(P<0.05)。结论神经内镜小切口锁孔治疗脑转移瘤能明显缩短手术时间、出院时间,提高患者术后短期生存质量,降低并发症发生率,在临床中有明显推广应用价值。Objective To Analyze the neuroendoscopic small incision keyhole approach for the treatment of brain metastases,and to explore its clinical application value.Methods A total of 72 patients with brain metastases admitted to our hospital from January 2016 to December 2019 were selected as the research objects,and randomly divided into the control group and the observation group,with 36 cases in each.The control group used conventional microscopic surgery,and the observation group used neuroendoscopic small incision keyhole approach.The operation time,discharge time,and complication rate of the two groups were compared.The KPS quality of life score was used to evaluate the postoperative follow-up and compare analysis.Results The average operation time of the observation group was(1.8±0.6)hours,the average discharge time was(6.3±1.7)days,and the complication rate was 13%(4/32);the average operation time of the control group was(2.9±1.3)hours,and the average discharge time was(9.6±1.5)days,the complication rate was 28%(9/32);there was a significant difference between the two groups(all P<0.05).The KPS scores of the observation group were 91.1±3.6 and 78.8±6.2 for the first month after the operation,and the KPS scores of the control group were 82.8±5.3 and 75.2±4.5.There was a significant difference in the quality of life between the two groups in the first month after the operation(P<0.05).Conclusions Neuroendoscopic small incision keyhole treatment of brain metastases can significantly shorten the operation time and discharge time,improve the short-term quality of life of patients after surgery,and reduce the incidence of complications.It has obvious clinical application value.

关 键 词：肿瘤转移 脑/外科学 神经内镜小切口锁孔入路 显微镜手术 

分 类 号：R47[医药卫生—护理学]