咳嗽变异性哮喘诊断和治疗研究进展  

Research Progress of Diagnosis and Treatment of Cough Variant Asthma

作　　者：钟剑辉 吴峰 ZHONG Jianhui;WU Feng(Guangdong Medical University,Zhanjiang 524000,China;Department of Respiratory,Huizhou Third People's Hospital,Huizhou 516000,China)

机构地区：[1]广东医科大学,广东省湛江市524000 [2]广东省惠州市第三人民医院呼吸内科,516000

出　　处：《实用心脑肺血管病杂志》2024年第6期1-6,共6页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：广东省卫生健康适宜技术推广项目(793)。

摘　　要：咳嗽变异性哮喘(CVA)是一种特殊类型的哮喘,以咳嗽为唯一或主要临床表现,因其在自然病程下可出现喘息、气促症状,因此常被认为是典型哮喘的初始阶段。吸入性糖皮质激素(ICS)单独使用或ICS联合长效β2受体激动剂是CVA的主要治疗方法。本文结合各国临床指南及近期研究新动态,介绍了CVA的病因、临床表现、病理生理改变及其机制、诊断方法、治疗策略及疗程、患者预后及其影响因素,以期为CVA的临床诊疗提供参考。Cough variant asthma(CVA)is a special type of asthma in which cough is the only or main symptom,and is often considered the initial stage of typical asthma because of wheezing and shortness of breath that occur in the natural course of the disease.Inhaled glucocorticoids(ICS)alone or ICS in combination with long acting beta 2-agonists are the primary treatment for CVA.Based on the clinical guidelines of various countries and recent research developments,this paper introduced the etiology,clinical manifestations,pathophysiological changes and their mechanisms,diagnostic methods,treatment strategies and courses,prognosis and influencing factors of CVA,in order to provide reference for the clinical diagnosis and treatment of CVA.

关 键 词：哮喘 咳嗽变异性哮喘 综述 

分 类 号：R256.12[医药卫生—中医内科学]