理中汤加味治疗小儿抗生素相关腹泻脾胃虚寒证的临床效果  

Clinical Effect of Lizhong Decoction on Spleen and Stomach Deficiency Cold Syndrome in Children with Antibiotic-related Diarrhea

作　　者：付慧 朱慧[2] FU Hui;ZHU Hui(Department of Pediatrics,Changzhou Second People's Hospital Affiliated to Nanjing Medical University,Changzhou,Jiangsu Province,213000 China;Department of Pediatrics,Nantong Hospital of Traditional Chinese Medicine,Nantong,Jiangsu Province,226001 China)

机构地区：[1]南京医科大学附属常州第二人民医院儿科,江苏常州213000 [2]南通市中医院儿科,江苏南通226001

出　　处：《系统医学》2024年第7期10-13,共4页Systems Medicine

基　　金：南通市卫生健康委员会科研课题专项(QNZ2022022)。

摘　　要：目的探讨理中汤加味治疗小儿抗生素相关腹泻脾胃虚寒证的临床效果。方法选取2023年1—6月南通市中医院收治的50例小儿抗生素相关腹泻脾胃虚寒证患儿作为研究对象,根据随机数表法分为两组,每组25例,对照组予以双歧杆菌三联活菌散口服治疗,观察组在对照组基础之上另予以理中汤加味治疗。比较两组临床疗效、中医证候积分、日均腹泻次数及腹泻持续时间。结果治疗1周,观察组临床总有效率为100.00%,高于对照组的76.00%,差异有统计学意义(χ^(2)=4.735,P<0.05);观察组各项中医证候积分均低于对照组,差异有统计学意义(P均<0.05)。治疗后72 h,观察组日均腹泻次数少于对照组,腹泻持续时间较对照组短,差异有统计学意义(P均<0.05)。结论理中汤加味治疗小儿抗生素相关腹泻脾胃虚寒证临床疗效显著,促进症状改善,缩短腹泻时间。Objective To investigate the clinical effect of Lizhong Decoction in the treatment of spleen and stomach deficiency cold syndrome in children with antibiotic-related diarrhea.Methods Fifty children with spleen and stomach deficiency cold syndrome with antibiotic-related diarrhea treated in Nantong Hospital of Traditional Chinese Medicine from January to June 2023 were selected as the study objects,and divided into two groups according to random number table method,with twenty-five cases in each group.The control group was given oral treatment of bifidobacterium triple live powder,and the observation group was given flavoured treatment of Lizhong Decoction on the basis of the control group.The clinical efficacy,traditional Chinese medicine(TCM)syndrome score,daily frequency and duration of diarrhea were compared.Results After 1 week of treatment,the total effective rate of the observation group was 100.00%,significantly higher than 76.00% of the control group,and the difference was statistically significant(χ^(2)=4.735,P<0.05).The scores of TCM syndrome in the observation group were lower than those in the control group,and the difference was statistically significant(all P<0.05).After 72 h of treatment,the average daily frequency of diarrhea in observation group was less than that in control group,and the duration of diarrhea was shorter than that in control group,and the difference was statistically significant(both P<0.05).Conclusion The clinical effect of Lizhong Decoction is significant in the treatment of spleen and stomach deficiency cold syndrome in children with antibiotic related diarrhea,promoting the improvement of symptoms,shortening the time of diarrhea.

关 键 词：小儿抗生素相关腹泻 脾胃虚寒证 理中汤加味方 临床效果 

分 类 号：R725.7[医药卫生—儿科]