慢性阻塞性肺疾病患者血清IL-2、IL-33、TNF-α变化的研究进展  

Progress in the Study of Changes in Serum IL-2,IL-33,and TNF-αin Patients with Chronic Obstructive Pulmonary Disease

作　　者：龙宇 原晋 张野 LONG Yu;YUAN Jin;ZHANG Ye(Department of Respiratory and Critical Care Medicine,Tongren People's Hospital,Tongren,Guizhou Province,554300 China)

机构地区：[1]铜仁市人民医院呼吸与危重症医学科,贵州铜仁554300

出　　处：《系统医学》2024年第7期195-198,共4页Systems Medicine

摘　　要：慢性阻塞性肺疾病是呼吸系统疾病中最为常见的一种疾病,是以气流受阻为特征的一种疾病,随着空气污染的加剧以及人口老龄化的发展,慢性阻塞性肺疾病的发病率呈现不断升高的趋势,且病死率也在不断上升,对人类健康造成极大威胁。多数研究表明,慢性阻塞性肺疾病发生与发展与众多炎症因子有关,炎症因子的变化对病情具有一定的指示作用。对炎症因子的早期监测,控制其变化对于缓解病情的发展具有重要价值。Chronic obstructive pulmonary disease is one of the most common respiratory diseases,which is characterized by airflow obstruction.With the aggravation of air pollution and the development of the aging population,the incidence of chronic obstructive pulmonary disease has shown a rising trend and the mortality rate is also increasing,which poses a great threat to human health.Numerous studies have shown that the occurrence and development of chronic obstructive pulmonary disease are related to numerous inflammatory factors,and that changes in inflammatory factors are indicative of the disease.Early monitoring of inflammatory factors and control of their changes are of great value in alleviating the progression of the disease.

关 键 词：阻塞性肺疾病 白细胞介素-2 白细胞介素-33 肿瘤坏死因子-α 免疫应答 巨噬细胞 

分 类 号：R563[医药卫生—呼吸系统]