中高能重离子束全径迹辐照材料和细胞的实验装置设计及效应分析  

Experimental Design and Effects Analysis of Full-Track Irradiation Materials and Cells Using Mid-high Energy Heavy Ion Beams

作　　者：李兴林[1] 曲颖[2] 孙曙光 Li Xinglin;Qu Ying;Sun Shuguang(School of Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China;Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou 730000,China;Anhui Simutang Biotechnology Development Co.,Ltd.,Maanshan 243000,China)

机构地区：[1]天津科技大学,天津300457 [2]中国科学院近代物理研究所,甘肃兰州730000 [3]安徽思母塘生物技术发展有限公司,安徽马鞍山243000

出　　处：《广东化工》2024年第7期1-3,16,共4页Guangdong Chemical Industry

基　　金：中国科学院兰州重离子加速器国家实验室培育项目(HIR2021PY013)。

摘　　要：中高能重离子束注入生物材料的径迹显著深于生物靶,且不同径迹点上的剂量分布、理化效应等又大不相同,所以,同一靶点通常不可能接受所有理化因子的作用(即全径迹辐照)。本实验设计思路:基于CR-39核径迹探测手段,在纯水介质中验证全径迹辐照综合效应特征;通过沿径迹上连续逆向移动靶材料或细胞培养液,以探究全径迹的辐照效应。最后,与对照组相比较,揭示重离子束全径迹的辐照效应及其潜在的分子改性、细胞改良和发酵工程等方面的应用价值。On the one hand,both the track of med-high energy heavy ion beams implanted into biological materials is significantly deeper than that of target materials,on the other hand,the dose distribution and physic-chemical effects at different track points are quite different,so it is usually impossible for the same target point to accept irradiation form all physical and chemical effects(ie full-track irradiation).The design concept of this experiment is:based on the CR-39 nuclear track detection method,verify the comprehensive effect characteristics of full-track irradiation in pure water medium;and exploring the irradiation effect of the full-track by continuously moving target materials or cells in the opposite direction along the track.Finally,compared with the control groups,the full-track irradiation effect of heavy ion beams and its potential application value were revealed such as molecular-modification,cell improvement and ferment engineering.

关 键 词：重离子束 全径迹辐照 材料 细胞 装置设计 效应分析 

分 类 号：TL13[核科学技术—核能科学] Q345[生物学—遗传学]