老年患者临床常见药物不良反应分析  

Analysis of Common Clinical Adverse Drug Reactions in Elderly Patients

作　　者：陈艳娜 Chen Yanna(Jiangmen Wuyi Hospital of Traditional Chinese Medicine Enping Branch,Enping 529400,Guangdong Province,China)

机构地区：[1]江门市五邑中医院恩平分院,广东恩平529400

出　　处：《中外医药研究》2024年第10期3-5,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析老年临床常见药物不良反应(ADR).方法:选取2022年1月—2023年6月江门市五邑中医院恩平分院收治的老年患者50例作为研究对象.回顾性分析患者病历资料,统计患者的药物治疗记录及ADR发生情况,总结安全用药的措施.结果:50例老年患者均发生了ADR,其中,60~65岁患者ADR发生率为30.00%(15/50),>65岁患者ADR发生率为70.00%(35/50);50例老年患者发生的ADR类型中,皮肤及其附件损害占比最高(48.00%),胃肠道反应次之,心血管系统反应、神经系统反应、全身性损害占比均较低;上报科室中,内科占比最高(96.00%);ADR主要药物中抗菌药物占比最高(40.00%),中药注射剂次之,非甾体抗炎药、降压药、其他类药物占比较低;给药途径主要为静脉滴注(78.00%),口服给药次之.结论:老年患者ADR发生率较高,尤其在>65岁群体中更为显著,且以皮肤及其附件损害、胃肠道和心血管系统反应为主.医务人员对老年患者进行治疗时,需加强对ADR的监控和管理,特别是在内科领域,以提高治疗的安全性和有效性.Objective:To analyze the common clinical adverse drug reaction(ADR)of the elderly.Methods:Fifty elderly patients admitted to Jiangmen Wuyi Hospital of Traditional Chinese Medicine Enping Branch from January 2022 to June 2023 were selected as the study objects.The medical records of patients were retrospectively analyzed,the drug treatment records and ADR occurrence of patients were statistically analyzed,and the measures for safe drug use were summarized.Results:ADR occurred in all 50 elderly patients,among which the incidence of ADR was 30.00%(15/50)in patients aged 60-65 years and 70.00%(35/50)in patients aged>65 years;among the ADR types of 50 elderly patients,skin and accessory damage accounted for the highest proportion(48.00%),followed by gastrointestinal reaction,cardiovascular system reaction,nervous system reaction and systemic damage accounted for a lower proportion;internal medicine accounted for the highest proportion(96.00%);antibacterial drugs accounted for the highest proportion(40.00%)in ADR,followed by traditional Chinese medicine injection,non-steroidal anti-inflammatory drugs,antihypertensive drugs,other drugs accounted for a relatively low proportion;the main route of administration was intravenous drip(78.00%),followed by oral administration.Conclusion:The incidence of ADR is higher in elderly patients,especially in the age group>65 years,and the ADR is mainly caused by skin and accessory damage,gastrointestinal tract and cardiovascular system reactions.It is necessary to strengthen the monitoring and management of ADR when medical staffs treat elderly patients,especially in the field of internal medicine,to improve the safety and effectiveness of treatment.

关 键 词：老年患者 药物不良反应 安全用药 

分 类 号：R544.1[医药卫生—心血管疾病]