加味痔科硝矾洗剂联合微波治疗对混合痔患者术后疼痛、创面恢复及炎症应激反应的影响  

Effect of modified Zhike Xiaofan Lotion combined with microwave treatment on postoperative pain,wound recovery and inflammatory stress response in patients with mixed hemorrhoids

作　　者：王成飞 钱雄杰 陈银 王丽萍 WANG Cheng-fei;QIAN Xiong-jie;CHEN Yin(Zhejiang Chinese Medical University,Hangzhou(310053),China)

机构地区：[1]浙江中医药大学,杭州310053 [2]湖州市吴兴区中西医结合医院肛肠科,浙江湖州313000

出　　处：《中国中西医结合外科杂志》2024年第3期386-390,共5页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:观察加味痔科硝矾洗剂联合微波治疗对混合痔患者术后疼痛、创面恢复及炎症应激反应的影响。方法:选取本院2022年1月—2022年12月收治的外剥内扎术混合痔患者120例,并随机分为三组,每组40例,其中对照1组行微波治疗;对照2组行微波联合温水坐浴治疗;联合组行微波+温水坐浴+加味痔科硝矾洗剂熏洗治疗。比较三组疼痛、水肿、渗液情况、炎症因子水平及肛门功能。结果:术后第3及第7天,联合组疼痛程度轻于对照1组,差异有统计学意义(P<0.05)。术后第3及第7天,联合组水肿、渗液评分均低于其他两组,差异有统计学意义(P<0.05);术后第7天,对照2组水肿及渗液评分低于对照1组,差异有统计学意义(P<0.05)。术后第3及第7天,联合组C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及降钙素原(PCT)水平低于其他两组,差异有统计学意义(P<0.05);对照2组CRP、TNF-α、PCT水平低于对照1组,差异有统计学意义(P<0.05)。术后第7天,联合组肛管静息压、收缩压、舒张压高于其他两组,差异有统计学意义(P<0.05),肛管高压带长度短于其他两组,差异有统计学意义(P<0.05)。结论:混合痔患者术后采用加味痔科硝矾洗剂联合微波、温水坐浴可显著缓解术后疼痛、水肿及渗液,从而改善炎症因子水平,促进肛门功能恢复。Objective To observe the effect of modified Zhike Xiaofan Lotion combined with microwave treatment on postoperative pain,wound recovery and inflammatory stress response in patients with mixed hemorrhoids.Methods 120 patients with mixed hemorrhoids who underwent external dissection and internal ligation in the hospital from January to December 2022 were selected and randomly divided into control group 1(40 cases,microwave treatment),control group 2(40 cases,microwave treatment and sitz bath with warm water)and combination group(40 cases,microwave treatment and sitz bath with warm water combined with fumigation and washing with modified Zhike Xiaofan Lotion).Pain degree,edema status,exudation,inflammatory factor levels,and anal function were compared among the three groups.Results On day 3 and day 7 after surgery,combination group had milder pain than control group 1(P<0.05).The scores for edema and exudate were lower than those of two control groups(P<0.05).On day 7 after surgery,the scores for edema and exudate of control group 2 were lower than those of control group 1(P<0.05).On day 3 and day 7 after surgery,the levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)and procalcitonin(PCT)in combination group were lower than those in two control groups(P<0.05).Meanwhile,levels in control group 2 were lower than those in control group 1(P<0.05).On day 7 after surgery,anal resting pressure,systolic pressure and diastolic pressure of combination group were higher than those of two control groups(P<0.05).The length of anal high-pressure zone was smaller than that of two control groups(P<0.05).Conclusion Modified Zhike Xiaofan Lotion combined with microwave treatment and sitz bath with warm water can significantly alleviate postoperative pain,edema and exudation in patients with mixed hemorrhoids,improve the levels of inflammatory factors,and promote the recovery of anal function.

关 键 词：混合痔 加味痔科硝矾洗剂 微波治疗 疼痛 

分 类 号：R657.18[医药卫生—外科学]