5.0T MRI测量健康成人海马结构亚区体积  

5.0T MRI measurement of hippocampal formationsubfield volumes in healthy adults

作　　者：王振松 刘建宪 李章柱 姜相森 阴祖栋[1] 于磊[1] 郭源[1] 李正义[1] 张茜[1] 甘洁[1] WANG Zhensong;LIU Jianxian;LI Zhangzhu;JIANG Xiangsen;YIN Zudong;YU Lei;GUO Yuan;LI Zhengyi;ZHANG Qian;GAN Jie(Department of Radiology,Shandong Provincial Third Hospital,Shandong University,Jinan 250031,China)

机构地区：[1]山东大学附属山东省立第三医院影像中心,山东济南250031

出　　处：《中国医学影像技术》2024年第5期648-652,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察5.0T MRI测量健康成人海马结构(HF)亚区体积的价值。方法前瞻性对23名健康成人志愿者以5.0T及3.0T MR仪采集高分辨T1WI;利用FreeSurfer软件将HF自动分为38个亚区,测量各亚区体积,比较基于5.0T与3.0T MR T1WI测值,并分析其相关性。结果基于5.0T与3.0T T1WI所测双侧海马尾、左侧旁下托、左侧海马分子层头、左侧颗粒细胞-分子层-齿状回头、右侧颗粒细胞-分子层-齿状回体、左侧阿蒙角(CA)1头、左侧CA3头、左侧CA4头、右侧海马伞及左侧海马杏仁核过渡区体积差异均有统计学意义(P均<0.05)。基于5.0T与3.0T T1WI所测HF各亚区体积均呈中、高度正相关(r均>0.5,P均<0.01)。结论5.0T MRI可用于测量成人海马结构亚区体积。Objective To observe the value of 5.0T MRI in measuring the volumes of hippocampal formation(HF)subfields in healthy adults.Methods Cranial high-resolution TIWI were prospectively obtained in 23 healthy adult volunteers using 5.0T and 3.0T MR scanners,respectively.HF was divided into 38 subfields,and then the volume of each subfield was measured using FreeSurfer software.The volumes of HF subfield based on 5.0T and 3.0T MR T1WI were compared,and the correlations of the outcomes were analyzed.Results Significant differences of the volumes of bilateral hippocampal tails,left parasubiculum,left molecular layer of hippocampal head,left granular cell-molecular layer-dentate gyrus head,right granular cell-molecular layer-dentate gyrus body,left cornu Ammonis(CA)1 head,left CA3 head,left CA4 head,right fimbria of hippocampus and left hippocampus amygdala transition area were found between 5.0T and 3.0T T1WI(all P<0.05).The volumes of HF subfields measured based on 5.0T and 3.0T T1WI were moderately to highly positively correlated(all r>0.5,all P<0.01).Conclusion 5.0T MRI could be used to measure the volume of HF subfield in adults.

关 键 词：磁共振成像 前瞻性研究 海马 体积测量 

分 类 号：R323.1[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]