机构地区:[1]Tianjin Key Laboratory of Retinal Functions and Diseases,Tianjin Branch of National Clinical Research Center for Ocular Disease,Eye Institute and School of Optometry,Tianjin Medical University Eye Hospital,Tianjin 300384,China [2]Ophthalmology Department of People’s Hospital of Hotan District,Hotan 848199,Xinjiang Uygur Autonomous Region,China
出 处:《International Journal of Ophthalmology(English edition)》2024年第6期1058-1065,共8页国际眼科杂志(英文版)
基 金:Supported by Tianjin Higher Education Commission Science and Technology Development Fund Project(No.2022ZD057);Tianjin Binhai New Area Health Commission Science and Technology Project(No.2022BWKZ003);Tianjin Key Laboratory of Retinal Function and Disease Open Project(No.2021tjswmm002);Tianjin Health Researh(No.TJWJ2023ZD002);General Project of Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2020D01A06);Special Fund for Youth of Clinical Research Center in Tianjin Medical University Eye Hospital(No.2020QN02);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A)。
摘 要:AIM:To analyze and compare the differences among ocular biometric parameters in Han and Uyghur populations undergoing cataract surgery.METHODS:In this hospital-based prospective study,410 patients undergoing cataract surgery(226 Han patients in Tianjin and 184 Uyghur patients in Xinjiang)were enrolled.The differences in axial length(AL),anterior chamber depth(ACD),keratometry[steep K(Ks)and flat K(Kf)],and corneal astigmatism(CA)measured using IOL Master 700 were compared between Han and Uyghur patients.RESULTS:The average age of Han patients was higher than that of Uyghur patients(70.22±8.54 vs 63.04±9.56y,P<0.001).After adjusting for age factors,Han patients had longer AL(23.51±1.05 vs 22.86±0.92 mm,P<0.001),deeper ACD(3.06±0.44 vs 2.97±0.37 mm,P=0.001),greater Kf(43.95±1.40 vs 43.42±1.69 D,P=0.001),steeper Ks(45.00±1.47 vs 44.26±1.71 D,P=0.001),and higher CA(1.04±0.68 vs 0.79±0.65,P=0.025)than Uyghur patients.Intra-ethnic male patients had longer AL,deeper ACD,and lower keratometry than female patients;however,CA between the sexes was almost similar.In the correlation analysis,we observed a positive correlation between AL and ACD in patients of both ethnicities(rHan=0.48,rUyghur=0.44,P<0.001),while AL was negatively correlated with Kf(rHan=-0.42,rUyghur=-0.64,P<0.001)and Ks(rHan=-0.38,rUyghur=-0.66,P<0.001).Additionally,Kf was positively correlated with Ks(rHan=0.89,rUyghur=0.93,P<0.001).CONCLUSION:There are differences in ocular biometric parameters between individuals of Han ethnicity in Tianjin and those of Uyghur ethnicity in Xinjiang undergoing cataract surgery.These ethnic variances can enhance our understanding of ocular diseases related to these parameters and provide guidance for surgical procedures.
关 键 词:ocular biometric parameters IOL Master 700 ethnic difference
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